46207-82-3Relevant academic research and scientific papers
Weak, bidentate chelating group assisted cross-coupling of C(sp3)-H bonds in aliphatic acid derivatives with aryltrifluoroborates
Cai, Zhihua,Li, Shangda,Gao, Yuzhen,Fu, Lei,Li, Gang
, p. 12766 - 12769 (2018)
A protocol of Pd(ii)-catalyzed, weak bidentate directing group assisted β-C(sp3)-H activation/cross-coupling with organoboron reagents has been achieved, affording arylation of aliphatic acid derivatives that contain α-hydrogen atoms in moderate to good yields. The potential of this method for an asymmetric β-C(sp3)-H arylation via desymmetrization was also presented.
Further studies on the metabolism of carbidopa, (-) L α hydrazino 3,4 dihydroxy α methylbenzenepropanoic acid monohydrate, in the human, rhesus monkey, dog, and rat
Vickers,Stuart,Hucker,VandenHeuvel
, p. 134 - 138 (2007/10/12)
Major urinary metabolites of carbidopa were identified. Estimates were made based on the recovery of radioactivity or by GLC analysis of pooled urine of the amounts of the urinary metabolites II (2 methyl 3' methoxy 4' hydroxy phenyl propionic acid), III
