6317-50-6

Basic information

• Product Name: 3-(3-HYDROXY-PHENYL)-2-METHYL-ACRYLIC ACID
• Synonyms: 2-Propenoic acid, 3-(3-hydroxyphenyl)-2-methyl-
• CAS NO: 6317-50-6
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.18
• Mol File: 6317-50-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 369.4°C at 760 mmHg
• Flash Point: 191.4°C
• Appearance: /
• Density: 1.274g/cm³
• Vapor Pressure: 4.15E-06mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 3-(3-HYDROXY-PHENYL)-2-METHYL-ACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-HYDROXY-PHENYL)-2-METHYL-ACRYLIC ACID(6317-50-6)
• EPA Substance Registry System: 3-(3-HYDROXY-PHENYL)-2-METHYL-ACRYLIC ACID(6317-50-6)

Safety Data

• Hazardous Substances Data: 6317-50-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10O3/c1-7(10(12)13)5-8-3-2-4-9(11)6-8/h2-6,11H,1H3,(H,12,13)/b7-5-

Upstream product

• 137-40-6 sodium proprionate 
• 100-83-4 meta-hydroxybenzaldehyde 
• 516-05-2 methyl-propanedioic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 102541-54-8 3-(3-hydroxy-2,4,6-triiodo-phenyl)-2-methyl-propionic acid 
• 46207-82-3 3-(3-hydroxyphenyl)-2-methylpropanoic acid 

Relevant articles and documents

Synthesis of Albicidin Derivatives: Assessing the Role of N-terminal Acylation on the Antibacterial Activity

The peptide antibiotic albicidin, which is synthesized by the plant pathogenic bacterium, Xanthomonas albilineans, represents the most prominent member of a new class of antibacterial gyrase inhibitors. It shows remarkable antibacterial activities against Gram-positive and Gram-negative microorganisms. Its unique structure potentially represents a new lead structure for the development of an antibacterial drug. Here we report the synthesis of 14 albicidin derivatives with structural variations at the N-terminus, primarily investigating the effects of variation of cinnamoyl, phenylpropanoyl, and benzoyl residues. Gyrase inhibition in vitro and determination of minimal inhibitory concentrations were assessed in parallel. Activities in a nanomolar range and the importance of N-acylation were demonstrated.