46255-82-7Relevant academic research and scientific papers
Synthesis of a dihydroquinoline based merocyanine as a 'naked eye' and 'fluorogenic' sensor for hydrazine hydrate in aqueous medium and hydrazine gas
Vijay,Nandi,Samant, Shriniwas D.
, p. 30712 - 30717 (2014)
1,2,2,4-Tetramethyldihydroquinoline (TMDQ) is formylated at the 6-position and the resulting quinoline aldehyde is condensed with 3-methyl-1-phenyl-1H- pyrazol-5(4H)-one to obtain a merocyanine 6-pyrazolinyl TMDQ. The merocyanine is a selective and sensitive sensor for hydrazine hydrate in aqueous ethanolic medium and also for hydrazine gas. The merocyanine detects hydrazine hydrate selectively in less than 5 s over other amines, anions, and metals. The detection can be done simply by the naked eye and quantification can be done by absorbance/fluorescence spectroscopy. Hydrazine hydrate as well as hydrazine gas can be detected by the TLC plate technique.
Laser flash photolysis study of the decay kinetics of carbocations of 1,2,2,4-tetramethyl-1,2-dihydroquinoline in the porous glass in the presence of methanol
Levin,Nekipelova,Khodot
, p. 2312 - 2316 (2005)
The efficiency of formation and the decay kinetics of carbocations formed under the photolysis of 1,2,2,4-tetramethyl-1,2-dihydroquinoline in methanol and in a porous glass filled with methanol or dried in air or in vacuo were studied by the laser flash photolysis techniques. In MeOH, the carbocations recombine via the second-order law in the reaction with the MeO- anion formed in an equimolar amount and decay via the first-order law in the reaction with the solvent with rate constants of 3·108 L mol-1 s-1 and 1.4·103 s-1, respectively. When the solution is placed into the porous glass, no recombination of the carbocations with MeO- is observed, and the reaction with the solvent is somewhat inhibited (rate constant 8·102 s-1). More than tenfold inhibition of the reaction of the carbocations with methanol is observed on going to a monolayer of MeOH on the surface. The main route of carbocation decay in the porous glass dried in vacuo is the geminate recombination with the SiO groups. The corresponding kinetics is described in terms of the model of freely diffusing reactants.
Synthesis of a dihydroquinoline based fluorescent cyanine for selective, naked eye, and turn off detection of Fe3+ ions
Vijay,Nandi,Samant, Shriniwas D.
, p. 49724 - 49729 (2016/07/06)
A cyanine dye was synthesized by condensing 6-formylated 1,2,2,4-tetramethyl-1,2-dihydroquinoline (TMDQ) and 1,7-dimethyl-2-phenylimidazo[1,2-a]pyridin-1-ium iodide. The probe was a selective sensor for ferric ions in aqueous ethanolic solution. The senso
CARBOPYRONONE COMPOUNDS USEFUL AS DIAGNOSTIC ADJUVANTS
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Page/Page column 106-107, (2016/01/27)
Described herein are fluorescent compounds and methods and comprising these compounds. The compounds disclosed herein are carbopyronine reagents that fluoresce in the red portion of the UV/VIS spectrum and provide bright fluorescence intensity, uniform cell staining, and good retention within live cells as well as low toxicity toward cells.
Multiple fluorescence ΔcIE and ΔrGB codes for sensing volatile organic compounds with a wide range of responses
Tian, Kaijun,Hu, Dehui,Hu, Rui,Wang, Shuangqing,Li, Shayu,Li, Yi,Yang, Guoqiang
supporting information; experimental part, p. 10052 - 10054 (2011/10/31)
A highly luminescent compound, stilbene-2,4-dimethyl-6-(1,2,2,4- tetramethyl-1,2-dihydroquinolin-6-yl)-1,3,5-s-triazine (MQT), exhibits solvent polarity-induced emission enhancement. A fluorescent sensor array was fabricated with MQT and porous polymer substrates. The colorimetric changes of the array exposed to VOCs can be readily distinguished by the naked eye. Post-processing procedures proved the high selectivity of the array for VOCs. The Royal Society of Chemistry 2011.
Novel Heteroarotinoids as Potential Antagonists of Mycobacterium bovis BCG
Brown, Chad W.,Liu, Shengquan,Klucik, Jozef,Berlin, K. Darrell,Brennan, Patrick J.,Kaur, Devinder,Benbrook, Doris M.
, p. 1008 - 1017 (2007/10/03)
A series of 15 heteroarotinoids has been prepared and evaluated for activity against Mycobacterium bovis BCG with the thiourea-containing isoxyl (7) (0.5 μg/mL) as the standard. 2,2,4-Trimethyl-2H-chromen-7-yl 4-(methoxycarbonyl)benzoate (8) displayed the most significant activity (2.0-4. 0 μg/mL) in terms of the lowest concentration (μg/mL) (MIC, minimum inhibitory concentration) required to produce a 99% reduction in the number of colonies on a plate as compared to that system free of the agent at the same dilution of the culture suspension. Ethyl 4-{[N-(2,2,4,4-tetramethylchroman-6-yl)thiocarbamoyl]amino}benzoate (9) and [(1E,3Z,5E)-1-aza-4-methyl-6-(1,2,2,4-tetramethyl(1,2-dihydroquinolyl))hexa-1,3, 5-trienyl]amino}aminomethane-1-thione (10) exhibited activity at 5.0-10.0 and 10.0-20.0 μg/mL, respectively, while the other examples had MIC values of 20 μg/mL or greater. The inhibitory ability of 8 may occur via the inhibition of mycolic acid synthesis in a like manner as found with 7, but this requires further study. The heteroarotinoids are the first examples to exhibit inhibitory ability against the growth of Mycobacterium bovis BCB.
N-ALKYLATION OF 2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE AND ITS DIMERIC ANALOGS UNDER INTERPHASE-CATALYSIS CONDITIONS
Shikhaliev, Kh. S.,Shmyreva, Zh. V.
, p. 898 - 900 (2007/10/02)
The possibility of the use of interphase catalysis for the synthesis of N-alkyl derivatives of 2,2,4-trimethyl-1,2-dihydroquinoline and its dimeric analogs was demonstrated.The effect of the nature of the alkylating agents on the reaction time and the yie
