462616-51-9

Basic information

• Product Name: Piperazine, 1-(1-methylethyl)-4-(4-nitrobenzoyl)-
• CAS NO: 462616-51-9
• Molecular Formula: C14H19N3O3
• Molecular Weight: 277.323
• Mol File: 462616-51-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-(1-methylethyl)-4-(4-nitrobenzoyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-(1-methylethyl)-4-(4-nitrobenzoyl)-(462616-51-9)
• EPA Substance Registry System: Piperazine, 1-(1-methylethyl)-4-(4-nitrobenzoyl)-(462616-51-9)

Safety Data

• Hazardous Substances Data: 462616-51-9(Hazardous Substances Data)

Upstream product

• 19678-58-1 4-Isopropylpiperidine 
• 62-23-7 4-nitro-benzoic acid 
• 72141-41-4 (4-nitro-phenyl)-piperazin-1-yl-methanone 
• 4318-42-7 1-(1-methylethyl)piperazine 
• 122-04-3 4-nitro-benzoyl chloride 

Relevant articles and documents

CYCLIN-DEPENDENT KINASE INHIBITING COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS

This invention is in the area of cell cycle inhibiting compounds for the treatment of disorders involving abnormal cellular proliferation, and include selective CDK2 inhibitors for medical therapy and their pharmaceutically acceptable salts and compositions.

Exploration of secondary and tertiary pharmacophores in unsymmetrical N,N′-diaryl urea inhibitors of soluble epoxide hydrolase

The impact of various secondary and tertiary pharmacophores on in vitro potency of soluble epoxide hydrolase (sEH) inhibitors based on the unsymmetrical urea scaffold 1 is discussed. N,N′-Diaryl urea inhibitors of soluble epoxide hydrolase exhibit subtle variations in inhibitory potency depending on the secondary pharmacophore but tolerate considerable structural variation in the second linker/tertiary pharmacophore fragment.