462647-76-3Relevant academic research and scientific papers
Convenient synthesis of Cbz-protected β-amino ketones by a copper-catalysed conjugate addition reaction
Wabnitz, Tobias C,Spencer, Jonathan B
, p. 3891 - 3894 (2002)
A convenient synthesis of Cbz-protected β-amino ketones is reported. Benzyl carbamates and α,β-unsaturated ketones furnish the conjugate addition products in the presence of a Cu(II) catalyst under mild conditions. Other weakly basic nitrogen nucleophiles
CAN-mediated oxidative cleavage of 4-aryl-3,4-dihydroxypiperidines
Chang, Meng-Yang,Lin, Chun-Yu,Pai, Chun-Li
, p. 2565 - 2568 (2007/10/03)
A CAN-mediated oxidative cleavage of 4-aryl-3,4-dihydroxypiperidines 2Aa-Be to β-amino carbonyl compounds 3Aa-Be and 4Aa-Be in different ratios is described. This facile strategy was also used to synthesize racemic fluoxetine (5).
