46277-44-5

Basic information

• Product Name: 1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione
• CAS NO: 46277-44-5
• Molecular Formula: C₁₀H₈N₂O₂
• Molecular Weight: 188.1827
• Mol File: 46277-44-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 377.7°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.367g/cm³
• Vapor Pressure: 6.62E-06mmHg at 25°C
• Refractive Index: 1.632
• CAS DataBase Reference: 1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione(46277-44-5)
• EPA Substance Registry System: 1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione(46277-44-5)

Safety Data

• Hazardous Substances Data: 46277-44-5(Hazardous Substances Data)

Usage

General Description

1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione is a chemical compound with a molecular formula C12H9NO2. It consists of a pyrrole ring with an attached pyridine group, and a carbonyl group at the 2,5 position. 1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione is often used as a building block in organic synthesis for the production of pharmaceuticals and agrochemicals. It is known for its potential biological activities and may have applications in medicinal chemistry for the development of new drugs. Additionally, it has been studied for its potential as an antifungal and antibacterial agent, and for its antioxidant properties. Overall, 1-(pyridin-4-ylmethyl)-1H-pyrrole-2,5-dione is a versatile compound with diverse potential applications in the fields of chemistry and medicine.

Upstream product

• 541-59-3 maleiimide 
• 586-95-8 pyridine-4-methanol 
• 108-31-6 maleic anhydride 
• 3731-53-1 4-(aminomethyl)pyridine 
• 7144-91-4 C₁₀H₁₀N₂O₃ 

Relevant articles and documents

Probing the in-air growth of large area of 3D functional structures into a 2D supramolecular nanoporous network

Surface-confined host-guest chemistry at the air/solid interface is used for trapping a functionalized 3D Zn-phthalocyanine complex into a 2D porous supramolecular template allowing the large area functionalization of an sp2-hybridized carbon-based substrate as evidenced by STM, resonance Raman spectroscopy, and water contact angle measurements.

Efficient method for the synthesis of functionalized basic maleimides

A three-step procedure involving Diels-Alder condensation of maleic anhydride with furane, formation of N-substituted imide upon reaction with appropriate diamine, and a final retro Diels-Alder regeneration of the maleic carbon-carbon double bond is proposed for an unequivocal synthesis of N-substituted basic maleimides. The novel method is characterized by mild reaction conditions, easy work-up, high yields, and no need for additional catalysis.

Multipolar interactions in the D pocket of thrombin: Large differences between tricyclic imide and lactam inhibitors

Two series of tricyclic inhibitors of the serine protease thrombin, imides (±)-1-(±)-8 and lactams (±)-9-(±)-13, were analysed to evaluate contributions of orthogonal multipolar interactions with the backbone CO moiety of Asn98 to the free enthalpy of pro