462871-29-0

Upstream product

• 122-52-1 triethyl phosphite 
• 462871-24-5 (S)-3-Benzyl-4-phenyl-oxazolidine 
• 100-52-7 benzaldehyde 
• 74879-43-9 (S)-2-Phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-ethanol 
• 20989-17-7 (2S)-2-phenylglycinol 
• 135357-90-3 (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol 
• 50-00-0 formaldehyd 
• 762-04-9 phosphonic acid diethyl ester 

Downstream Products

• 462871-49-4 {[Benzyl-((R)-2-chloro-2-phenyl-ethyl)-amino]-methyl}-phosphonic acid diethyl ester 
• 462871-65-4 ((2R,3S)-1-Benzyl-3-phenyl-azetidin-2-yl)-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

An efficient asymmetric synthesis of azetidine 2-phosphonic acids

Substituted azetidinic 2-phosphonates were prepared in diastereoisomerically and enantiomerically pure form, starting from readily available β-amino alcohols. This synthesis involved a three-step sequence: (i) N-alkylation of the starting amino alcohol wi

NMR and X-ray crystallographic studies of axial and equatorial 2-ethoxy-2-oxo-1,4,2-oxazaphosphinane

Condensation of (S)-(N-benzyl)-phenylglycinol with formaldehyde in the presence of diethylphosphite afforded hydroxyaminophosphonate (S)-3, which upon treatment with KH yielded a 97:3 mixture of the interesting, phosphorus-containing 2-ethoxy-2-oxo-1,4,2-