46322-66-1

Usage

Uses

Used in Oncology:
Procarbazine is used as an anticancer agent for the treatment of Hodgkin's disease and certain brain tumors. It functions by alkylate the DNA of cancer cells, which prevents them from growing and dividing, thus helping to control or reduce the size of tumors.
Used in Combination Chemotherapy:
In the field of oncology, procarbazine is often used in combination with other chemotherapy drugs. This combined approach is utilized to increase the overall effectiveness of treatment and to potentially overcome resistance that cancer cells may develop to single-agent therapies.

Upstream product

• 874-42-0 2,4-dichlorobenzaldeyhde 
• 79-17-4 aminoguanidine 
• 2582-30-1 aminoguanidine bicarbonate 

Downstream Products

• 185422-36-0 N¹-[1-(2,4-Dichloro-phenyl)-meth-(E)-ylidene]-4-phenyl-imidazole-1,2-diamine 

Relevant academic research and scientific papers

Synthesis, Antileishmanial Activity and In Silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes

Background: Leishmaniasis is a worldwide health problem, highly endemic in developing countries. Among the four main clinical forms of the disease, visceral leishmaniasis is the most se-vere, fatal in 95% of cases. The undesired side-effects from first-li

Synthesis of substituted 2-amino-1-arylidenaminoimidazoles and 1-arylidenaminoimidazo[1,2-a]imidazoles

A new method is proposed for the preparation of 2-amino-1-arylidenaminoimidazoles, which react with α-haloketones to give a series of 1-arylidenamino-3-acylmethyl-2-iminoimidazolines and 1-arylidenaminoimidazo[1,2-a]imidazoles depending on the conditions. 1997 Plenum Publishing Corporation.