463300-44-9

Basic information

• Product Name: (R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)pyrrolidin-2-one
• Synonyms: (R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)pyrrolidin-2-one
• CAS NO: 463300-44-9
• Molecular Weight: 523.725
• Mol File: 463300-44-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)pyrrolidin-2-one(463300-44-9)
• EPA Substance Registry System: (R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)pyrrolidin-2-one(463300-44-9)

Safety Data

• Hazardous Substances Data: 463300-44-9(Hazardous Substances Data)

Upstream product

• 138629-44-4 (R)-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-2-one 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 

Downstream Products

• 366479-75-6 (4S,5R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)-4-vinylpyrrolidin-2-one 
• 366479-74-5 (R)-5-[(tert-butyldiphenylsilyloxy)methyl]-1-(4-methoxybenzenesulfonyl)-2,5-dihydro-1H-pyrrol-2-one 

Relevant articles and documents

Design and synthesis of matrix metalloproteinase inhibitors guided by molecular modeling. Picking the S1 pocket using conformationally constrained inhibitors

Conformationally constrained MMP inhibitors based on a D-proline scaffold were designed using AutoDock as a modeling program. Thus a family of D-proline hydroxamic acids, having differentiated functionality at the site of binding to the S1 pock