4636-43-5

Upstream product

• 598-72-1 2-Bromopropionic acid 
• 2227-79-4 benzenecarbothioamide 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 1514677-61-2 (R)-5-methyl-2-phenyl-5-((R)-1-phenylallyl)thiazol-4(5H)-one 
• 1514677-63-4 (R)-5-((R)-1-(4-fluorophenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-65-6 (R)-5-((R)-1-(4-chlorophenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-66-7 (R)-5-((R)-1-(4-bromophenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-70-3 (R)-5-((R)-1-(4-trifluoromethylphenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-72-5 (R)-5-((R)-1-(4-methylphenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-73-6 (R)-5-((R)-1-(4-methoxyphenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-77-0 (R)-5-((R)-1-(4-naphthyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-79-2 (R)-5-((R)-1-(3,4-dichlorophenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-80-5 (R)-5-((R)-1-(3-indolyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 
• 1514677-81-6 (R)-5-((R)-1-(2-furyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one 

Relevant academic research and scientific papers

Enantioselective Synthesis of 5-Alkylated Thiazolidinones via Palladium-Catalyzed Asymmetric Allylic C-H Alkylations of 1,4-Pentadienes with 5 H-Thiazol-4-ones

A palladium-catalyzed, enantioselective allylic C-H alkylation of 1,4-pentadienes with 5H-thiazol-4-ones has been developed. Under the cooperative catalysis of a palladium complex of chiral phosphoramidite ligand and an achiral Br?nsted acid, a broad range of substituted 5H-thiazol-4-ones bearing sulfur-containing tertiary chiral centers were accessed from the allylic C-H alkylation in high levels of yields and enantioselectivities. Alkyl and aryl 1,4-pentadienes led to linear and branched allylation products, respectively.