463952-34-3Relevant academic research and scientific papers
Asymmetric synthesis of α,α-disubstituted α-amino alcohol derivatives
Nakamura, Tsuyoshi,Tsuji, Takashi,Iio, Yukiko,Miyazaki, Shojiro,Takemoto, Toshiyasu,Nishi, Takahide
, p. 2781 - 2792 (2006)
We herein report an asymmetric synthesis of α,α-disubstituted α-amino alcohol derivatives 3, key intermediates of a novel immunomodulator, using enzymatic desymmetrization of 2-alkyl-2-tert-butoxycarbonylamino-1,3-propanediols 1a and 1b. This method makes
