463961-43-5 Usage
General Description
3-(Bromomethyl)cyclobutanone is a chemical compound with the molecular formula C5H7BrO. It is a cyclobutanone derivative that contains a bromomethyl group attached to the cyclobutanone ring. 3-(Bromomethyl)cyclobutanone is primarily used as an intermediate in organic synthesis and in the production of pharmaceuticals. It is a versatile building block for the synthesis of a variety of organic compounds and has applications in the pharmaceutical and agrochemical industries. Additionally, 3-(Bromomethyl)cyclobutanone is a valuable reagent in the field of chemical research and can be used in the preparation of a wide range of organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 463961-43-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,3,9,6 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 463961-43:
(8*4)+(7*6)+(6*3)+(5*9)+(4*6)+(3*1)+(2*4)+(1*3)=175
175 % 10 = 5
So 463961-43-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H7BrO/c6-3-4-1-5(7)2-4/h4H,1-3H2
463961-43-5Relevant articles and documents
Synthesis of 1-amino-3-[(dihydroxyboryl)methyl]-cyclobutanecarboxylic acid as a potential therapy agent
Kabalka, George W.,Yao, Min-Liang
, p. 8280 - 8286 (2007/10/03)
A novel boronated aminocyclobutanecarboxylic acid (1) was synthesized for potential use in boron neutron capture therapy. Starting from the readily available 3-(bromomethyl)cyclobutanone ketal (4), several synthetic routes to 1 were evaluated. After sever
Synthesis of 2,4-methanoproline analogues via an addition-Intramolecular substitution sequence
Rammeloo, Thomas,Stevens, Christian V.,De Kimpe, Norbert
, p. 6509 - 6513 (2007/10/03)
A new two-step synthetic approach toward 3-(chloromethyl)cyclobutanone is described and used in the synthesis of 2,4-methanoproline analogues. The key step consists of a reversible addition of hydrogen cyanide onto the imines 12 in 50-74% yield under conditions that allow ring closure. 2-Alkyl-2-azabicyclo [2.1.1]hexane-1-carbonitriles 19, synthesized in four steps, can also be converted to the corresponding amines.
