463967-27-3Relevant academic research and scientific papers
In search of optically active γ-keto acetylenes via regioselective coupling of allenylidene groups and cyclic enolates
Cadierno, Victorio,Conejero, Salvador,Gamasa, M. Pilar,Gimeno, José,Falvello, Larry R.,Llusar, Rosa M.
, p. 3716 - 3726 (2002)
An efficient synthetic approach of γ-keto acetylenes based on the regio- and diastereoselective propargylic alkylation of 2-propyn-1-ols with methyl ketones was discussed. The synthetic methodology constituted an alternative to the well-known Nicholas cou
