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1-Iodo-1,1-difluoro-2-chloroethane, also known as C2H2ClF2I, is a halogenated organic compound characterized by the presence of one iodine, two fluorine, and one chlorine atom attached to a two-carbon chain. This colorless liquid is a derivative of ethylene, with the halogens replacing hydrogen atoms in the molecule. It is primarily used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and the presence of multiple halogens, it can be involved in various chemical reactions, such as nucleophilic substitutions and eliminations. However, it is important to handle 1-Iodo-1,1-difluoro-2-chloroethane with care, as it may pose health risks and environmental concerns due to its potential toxicity and persistence in the environment.

464-02-8

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464-02-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 464-02-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 464-02:
(5*4)+(4*6)+(3*4)+(2*0)+(1*2)=58
58 % 10 = 8
So 464-02-8 is a valid CAS Registry Number.

464-02-8Upstream product

464-02-8Downstream Products

464-02-8Relevant academic research and scientific papers

Radical addition of iodine monochloride to vinylidene fluoride

Kharroubi,Manséri,Améduri,Boutevin

, p. 145 - 153 (2007/10/03)

The radical addition of iodine monochloride to 1,1-difluoroethylene or vinylidene fluoride (VDF) leading to a ClCF2CH2I (I)/ClCH2CF2I (II) mixture is described. Four different ways of initiation (thermal, photochemical, presence of radical initiators or redox catalysts) were used and all of them led to a high amount (≥98%) of isomer (I). The percentages of (I) and (II) isomers were determined by 19F NMR and they were also deduced from those of ClCF2CH3 and ClCH2CF2H obtained by selective reduction of the iodine atom of the product mixture, by tributylstannane. The reactivity of ICl to VDF and the high proportion of isomer (I) were interpreted by means of a thermodynamical approach from the enthalpy of formation of (I) and (II), respectively, determined by semi-empirical computations. In addition, heats of formation of both isomers and interactions between the SOMO of radicals and the HOMO of the fluoroolefin show that the mechanism of such a reaction occurs via the addition of I· to the less fluorinated side of VDF.

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