46412-20-8Relevant academic research and scientific papers
Efficient Synthesis of Phenoxathiines via the Cascade C–H Hydroxylation–C–S Coupling–C–O Cyclization Reaction
Chao, Fei,Xu, Wen-Heng,Ren, Zhi-Lin,Wang, Long
, p. 2558 - 2561 (2019)
The ligand-free and simple cascade C–H hydroxylation–C–S coupling–C–O cyclization reaction has been used as the synthetic approach to disulfides and o-chloro-iodobenzenes using CuI as a catalyst. This approach provides an easy and convenient method of synthesis of phenoxathiin derivatives.
Synthesis of phenoxathiins and phenothiazines by aryne reactions with thiosulfonates
Hosoya, Takamitsu,Kanemoto, Kazuya,Sakata, Yuki,Yoshida, Suguru
, p. 593 - 596 (2020/05/19)
Novel synthetic methods for phenoxathiins and phenothiazines by aryne reactions are disclosed. We found that phenoxathiins were efficiently prepared by the reaction between aryne intermediates and S-(2-hydroxyaryl) 4-toluenethiosulfo-nates. A synthetic method for phenothiazines was also developed by the reaction of arynes with S-(2-aminoaryl) 4-toluenethiosulfonates.
Regioselective synthesis of phenoxathiin derivatives under transition-metal-free conditions
Hu, Fangdong,Zhao, Xin,Li, Yanqiu,Feng, Lei,Ma, Chen
, p. 966 - 970 (2013/05/09)
A simple and efficient method was developed for the synthesis of phenoxathiin derivatives. A range of 1,2-dihaloarenes or 1-halo-2-nitroarenes reacted with 2-sulfanylphenol to give the desired products in good-to-excellent yields. It is intriguing that 1-halo-2-nitroarenes containing electron-donating groups worked well as substrates in this reaction. Georg Thieme Verlag Stuttgart - New York.
