464178-61-8Relevant academic research and scientific papers
Selective conversion of O-succinimidyl carbamates to N-(O-carbamoyl)-succinmonoamides and ureas
Vasilevich, Natalya I.,Sachinvala, Navzer D.,Maskos, Karol,Coy, David H.
, p. 3443 - 3445 (2002)
N-Monoalkyl-O-succinimidyl carbamates reacted with primary and secondary amines to produce ureas. However, N,N-dialkyl-O-succinimidyl carbamates reacted with primary and secondary amines, via succinimide ring opening, to afford N-(O-carbamoyl)-succinmonoamide derivatives. This ring-opening trend was also true with hydroxy and alkoxy nucleophiles. Herein, general methods for the synthesis and NMR characterization of N-(O-carbamoyl)-succinmonoamides are reported.
1-Phenyl-4-carbamoyl piperazine compounds, process for preparation thereof and utilizations thereof
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, (2008/06/13)
The present invention relates to a novel piperazine compound represented by the following general formula (I): STR1 wherein X stands for a hydrogen or halogen atom, an alkoxy, carboxy or alkoxycarbonyl group or a group R3 CO-- in which R3
