464189-36-4

Basic information

• Product Name: (1R,5R)-5-(3'-methyl-2'-oxobutyl)-3-phenyl-1-trimethylsilyl-3-azabicyclo[3.1.0]hexane-2,4-dione
• CAS NO: 464189-36-4
• Molecular Weight: 343.498
• Mol File: 464189-36-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,5R)-5-(3'-methyl-2'-oxobutyl)-3-phenyl-1-trimethylsilyl-3-azabicyclo[3.1.0]hexane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,5R)-5-(3'-methyl-2'-oxobutyl)-3-phenyl-1-trimethylsilyl-3-azabicyclo[3.1.0]hexane-2,4-dione(464189-36-4)
• EPA Substance Registry System: (1R,5R)-5-(3'-methyl-2'-oxobutyl)-3-phenyl-1-trimethylsilyl-3-azabicyclo[3.1.0]hexane-2,4-dione(464189-36-4)

Safety Data

• Hazardous Substances Data: 464189-36-4(Hazardous Substances Data)

Upstream product

• 556-24-1 methyl 3-methylbutanoate 
• 211800-50-9 (1R,5S)-3-phenyl-1-trimethylsilyl-3-azabicyclo[3.1.0]hexane-2,4-dione 

Relevant articles and documents

Highly enantioselective synthesis of chiral imides and derived products via chiral base desymmetrisation

The enantioselective deprotonation of several ring-fused imides with a chiral base, followed by electrophilic quenching, gives a range of chiral products in good yield and in ≥91% ee. The absolute stereochemistry of two of the products was determined by X-ray crystallography. A number of the imide products were subjected to further, highly regioselective, transformations, including enolate substitution, reduction and thionation.