4650-82-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Furancarboxylic acid, tetrahydro-, (tetrahydro-2-furanyl)methyl ester is used as a solvent, intermediate, or raw material in the production of various pharmaceutical and agrochemical compounds. It plays a crucial role in the synthesis of these compounds, contributing to their development and effectiveness.
Used in Chemical Production:
In the chemical industry, 2-Furancarboxylic acid, tetrahydro-, (tetrahydro-2-furanyl)methyl ester is utilized as a solvent and intermediate in the manufacturing process of various chemical products. Its properties make it suitable for use in different chemical reactions and processes.
Used as a Flavoring Agent in Food and Beverage Applications:
2-Furancarboxylic acid, tetrahydro-, (tetrahydro-2-furanyl)methyl ester is also used as a flavoring agent in the food and beverage industry. Its slightly sweet, fruity odor makes it a valuable ingredient in creating unique and appealing flavors for various products.

Upstream product

• 97-99-4 Tetrahydrofurfuryl alcohol 
• 16874-33-2 tetrahydro-2-furancarboxylic acid 

Relevant academic research and scientific papers

Development of effective bidentate diphosphine ligands of ruthenium catalysts toward practical hydrogenation of carboxylic acids

Hydrogenation of carboxylic acids (CAs) to alcohols represents one of the most ideal reduction methods for utilizing abundant CAs as alternative carbon and energy sources. However, systematic studies on the effects of metal-to-ligand relationships on the catalytic activity of metal complex catalysts are scarce. We previously demonstrated a rational methodology for CA hydrogenation, in which CA-derived cationic metal carboxylate [(PP)M(OCOR)]+ (M = Ru and Re; P = one P coordination) served as the catalyst prototype for CA self-induced CA hydrogenation. Herein, we report systematic trial- and-error studies on how we could achieve higher catalytic activity by modifying the structure of bidentate diphosphine (PP) ligands of molecular Ru catalysts. Carbon chains connecting two P atoms as well as Ar groups substituted on the P atoms of PP ligands were intensively varied, and the induction of active Ru catalysts from precatalyst Ru(acac)3 was surveyed extensively. As a result, the activity and durability of the (PP)Ru catalyst substantially increased compared to those of other molecular Ru catalyst systems, including our original Ru catalysts. The results validate our approach for improving the catalyst performance, which would benefit further advancement of CA self-induced CA hydrogenation.

Studies on the Oxidation of Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside with Pyridinium Dichromate. Identification of Unexpected By-Products

Oxidation of methyl 2,3-O-isopropylidene-β-D-ribofuranoside (1a) with pyridinium dichromate yields, in addition to the expected methyl 2,3-O-isopropylidene-β-D-ribo-1,4-pentodialdofuranoside (1b), methyl 2,3-O-isopropopylidene-β-D-erythrosidurono-1,4-lactone (3) and the dimeric ester 1e.The structures of the latter compounds were determined by spectroscopic methods.A mechanistic scheme is proposed for their formation.