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1-(2-chlorobenzyl)urea is an organic compound with the chemical formula C8H9ClN2O. It is a white crystalline solid that is soluble in water and various organic solvents. 1-(2-chlorobenzyl)urea is primarily used as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the production of herbicides and other pesticides. The presence of the chlorobenzyl group in its structure provides it with unique reactivity and properties, making it a valuable building block in the development of various chemical products.

4654-63-1

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4654-63-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4654-63-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,5 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4654-63:
(6*4)+(5*6)+(4*5)+(3*4)+(2*6)+(1*3)=101
101 % 10 = 1
So 4654-63-1 is a valid CAS Registry Number.

4654-63-1Relevant academic research and scientific papers

Highly selective aldose reductase inhibitors. 1. 3-(Arylalkyl)-2,4,5- trioxoimidazolidine-1-acetic acids

Ishii,Kotani,Nagaki,Shibayama,Toyomaki,Okukado,Ienaga,Okamoto

, p. 1924 - 1927 (2007/10/03)

A series of 3-(arylalkyl)-2,4,5-trioxoimidazolidine-1-acetic acids (1) was prepared and tested for aldose reductase (AR) and aldehyde reductase (ALR) inhibitory activities. These compounds showed strong inhibitory activity against AR without significant inhibitory activity for ALR. The ratio of IC50(ALR)IC50(AR) was > 1000 in some compounds. On the basis of pharmacological tests such as the recovery of reduced motor nerve conduction velocity and toxicological profile, 3-(3-nitrobenzyl)-2,4,5- trioxoimidazolidine-1-acetic acid (NZ-314) was selected as the candidate for clinical development.

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