465514-33-4

Usage

Uses

Used in Pharmaceutical Synthesis:
(2-MORPHOLINOPHENYL)METHANOL is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its presence in the molecular structure of these compounds contributes to their bioactivity and therapeutic potential.
Used in Organic Chemistry Research:
In the field of organic chemistry, (2-MORPHOLINOPHENYL)METHANOL is utilized as a chiral auxiliary in asymmetric synthesis processes. Its stereochemical properties make it a valuable tool for enhancing the selectivity and yield of enantioselective reactions, which is crucial for the production of chiral drugs and other biologically active molecules.
Used in the Development of New Materials:
(2-MORPHOLINOPHENYL)METHANOL also plays a role in the development of new materials with unique properties. Its incorporation into the molecular structure of these materials can impart specific characteristics, such as improved stability, reactivity, or selectivity, which can be beneficial in various applications.

InChI:InChI=1/C11H15NO2/c13-9-10-3-1-2-4-11(10)12-5-7-14-8-6-12/h1-4,13H,5-9H2

Upstream product

• 58028-76-5 2-(morpholin-4-yl)benzaldehyde 
• 394-35-4 methyl 2-fluorobenzoate 
• 223560-37-0 methyl 2-morpholinobenzoate 

Downstream Products

• 110405-99-7 2-morpholinobenzyl chloride 
• 117323-27-0 4-{2-[1-(3-Methoxy-pyridin-2-yl)-1H-imidazol-2-ylsulfanylmethyl]-phenyl}-morpholine 
• 117323-81-6 2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole 
• 117323-22-5 4-{2-[1-(3-Methyl-pyridin-2-yl)-1H-imidazol-2-ylsulfanylmethyl]-phenyl}-morpholine 
• 117323-28-1 4-[2-(1-Pyridin-2-yl-1H-imidazol-2-ylsulfanylmethyl)-phenyl]-morpholine 

Relevant academic research and scientific papers

An efficient microwave-assisted solvent-free synthesis of pyrido-fused ring systems applying the tert-amino effect

Significant improvements in the synthesis of pyrido-fused heterocycles were observed when performing the reaction under solvent-free conditions, applying the tert-amino effect as the key ring closure methodology. An unexpected cyclization of ortho-(1′-aza

RECEPTOR FUNCTION REGULATING AGENT

An agent for regulating 14273 receptor function, which is useful as a preventing or treating drug for diabetes mellitus, hyperlipidemia or the like, is provided. An agent for regulating 14273 receptor function comprising a compound containing an aromatic ring and a group capable of releasing a cation.

2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6- tetrahydrocyclopent[d]imidazoles as a novel class of gastric H+/K+-ATPase inhibitors

Substituted 2-sulfinylimidazoles were synthesized and investigated as potential inhibitors of gastric H+/K+-ATPase. The 4,5-unsubstituted imidazole series 6-11 and the 1,4,5,6-tetrahydrocyclopent[d]imidazole series 12 were found to be potent inhibitors of the acid secretory enzyme H+/K+- ATPase. Structure-activity relationships indicate that the substitution of 2- pyridyl groups at the 1-position of the imidazole moiety combined with (2- aminobenzyl)sulfinyl groups at the 2-position leads to highly active compounds with a favorable chemical stability. Other substitution patterns in the imidazole moiety result in reducing biological activities. 2-[(2- Aminobenzyl)sulfinyl]-1-[2-(3-methylpyridyl)]-1,4,5,6- tetrahydrocyclopent[d]imidazole (12h, T-776) was selected for further development as a potential clinical candidate. Extensive study on the acid degradation of 12h indicates a mechanism of action different from that of omeprazole, the first H+/K+-ATPase inhibitor introduced to the market.