465519-02-2Relevant academic research and scientific papers
Total Synthesis of Macroviracin D (BA-2836-4)
Mlynarski, Jacek,Ruiz-Caro, Juliana,Fuerstner, Alois
, p. 2214 - 2222 (2007/10/03)
The first total synthesis of the complex glycolipid macroviracin D (BA-2836-4) (1) is described. This antivirally active metabolite isolated from the mycelium extracts of Streptomyces sp. BA-2836 incorporates a unique 46-membered macrodilactone motif deco
Structure Assignment, Total Synthesis, and Antiviral Evaluation of Cycloviracin B1
Fuerstner, Alois,Albert, Martin,Mlynarski, Jacek,Matheu, Maribel,DeClercq, Erik
, p. 13132 - 13142 (2007/10/03)
The first total synthesis of the antivirally active glycolipid cycloviracin B1 (1) is described. The approach is based on a two-directional synthesis strategy which constructs the C 2-symmetrical macrodiolide core of the target by an
Total synthesis of the antiviral glycolipid cycloviracin B1
Fuerstner, Alois,Mlynarski, Jacek,Albert, Martin
, p. 10274 - 10275 (2007/10/03)
The first total synthesis of the antiviral agent cycloviracin B1 (1) is described which provisionally establishes the hitherto unknown configuration of the chiral centers on the lateral fatty acid chains as (3R,19S,25R,3′R,17′S,23′R). Key steps en route t
