465528-50-1

Basic information

• Product Name: 2-{(1-(3-[4-chlorophenyl]propyl)aminocarbonyl)cyclopentylmethyl}-4-methoxybutyric acid tert-butyl ester
• Synonyms: 2-{(1-(3-[4-chlorophenyl]propyl)aminocarbonyl)cyclopentylmethyl}-4-methoxybutyric acid tert-butyl ester
• CAS NO: 465528-50-1
• Molecular Weight: 435.579
• Mol File: 465528-50-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{(1-(3-[4-chlorophenyl]propyl)aminocarbonyl)cyclopentylmethyl}-4-methoxybutyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{(1-(3-[4-chlorophenyl]propyl)aminocarbonyl)cyclopentylmethyl}-4-methoxybutyric acid tert-butyl ester(465528-50-1)
• EPA Substance Registry System: 2-{(1-(3-[4-chlorophenyl]propyl)aminocarbonyl)cyclopentylmethyl}-4-methoxybutyric acid tert-butyl ester(465528-50-1)

Safety Data

• Hazardous Substances Data: 465528-50-1(Hazardous Substances Data)

Upstream product

• 118756-03-9 1-[2-(tert-butoxycarbonyl)ethyl]-1-cyclopentanecarboxylic acid 
• 25468-86-4 3-(4'-fluorophenyl)propanenitrile 
• 3400-45-1 cyclopentanecarboxylic acid 
• 55666-43-8 tert-butyl 3-bromopropionate 
• 388631-29-6 1-[-2-(tert-Butoxycarbonyl)-4-methoxybutyl]Cyclopentanecarboxylic Acid 
• 101488-65-7 3-(4-fluorophenyl)propan-1-amine 

Relevant articles and documents

Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder

A series of substituted glutaramides were synthesised using Candoxatrilat 1 as a lead and evaluated for potency against neutral endopeptidase (NEP) as a potential treatment for female sexual arousal disorder (FSAD). In this paper, we describe studies in which we were able to increase NEP activity substantially over the levels reported for previous compounds from this programme by appropriate substitution in both the P1′ and P2′ regions. Optimisation led to the 4-chlorophenpropylamide S-30 which was selected as a candidate for further study.