465531-75-3Relevant academic research and scientific papers
A new, general entry to 3,5-unsubstituted 4-O-alkyl tetramates
Paintner, Franz F.,Metz, Marcel,Bauschke, Gerd
, p. 869 - 874 (2007/10/03)
A variety of 3,5-unsubstituted 4-O-benzyl tetramates 10 was prepared in good overall yield from methyl (E)-3-benzyloxy-4-oxobut-2-enoate 7 by a reductive amination-lactamization sequence. An efficient approach to this building block as well as to various 3-alkoxy analogues is presented.
