465532-55-2Relevant academic research and scientific papers
Functionalized alkyl and aryl diselenides as antimicrobial and antiviral agents: Synthesis and properties
Wojtowicz,Chojnacka,Mlochowski,Palus,Syper,Hudecova,Uher,Piasecki,Rybka
, p. 1235 - 1242 (2007/10/03)
The different dialkyl and diaryl diselenides with carbamoyl and sulfamoyl moieties 2, 3, 5 and other substituents in the ortho position of benzene ring 4, 7, 8 as well as derivatives of 1,2,4-benzoselenadiazine (6) were designed as antiviral and antimicrobial agents and synthesized. Some of them, particularly 8a and 8b, were found in the antiviral assay in vitro to be strong inhibitors of cytopathic activity encephalomyocarditis virus (EMCV). The compound 4a and 8a were found to have a broad spectrum of acivity against bacteria, yeasts and pathogenic fungi in vitro.
New heterocyclic selenenamides: 1,2,4-benzoselenadiazin-3(4H)-ones and 1,3,2-benzodiselenazoles
Kloc, Krystian,M?ochowski, Jacek,Osajda, Karol,Syper, Ludwik,Wójtowicz, Halina
, p. 4071 - 4074 (2007/10/03)
Two groups of selenium-containing heterocycles having new, unique 1,2,4-benzoselenadiazine and 1,3,2-diselenazole ring systems with an endocyclic selenenamide C-N moiety are presented. The first type was obtained by oxidative cyclization of 2,2′-diselenobis(phenylureas) and the second type by the reaction of 1,2-di(bromoseleno)benzene with primary amines.
