465617-04-3Relevant academic research and scientific papers
Parallel synthesis and evaluation of N-(1-phenylethyl)-5-phenyl-imidazole-2-amines as Na+/K+ ATPase inhibitors
Blass, Benjamin E.,Huang,Kawamoto, Richard M.,Li, Min,Liu, Song,Portlock, David E.,Rennells, William M.,Simmons, Melanie
, p. 1543 - 1545 (2000)
A series of N-(1-phenylethyl)-5-phenyl-imidazole-2-amines was prepared using solution-phase, parallel synthesis and evaluated for Na+/K+ ATPase inhibition. (C) 2000 Elsevier Science Ltd. All rights reserved.
Novel imidazole-based histamine H3 antagonists
Jablonowski, Jill A.,Ly, Kiev S.,Bogenstaetter, Michael,Dvorak, Curt A.,Boggs, Jamin D.,Dvorak, Lisa K.,Lord, Brian,Miller, Kirsten L.,Mazur, Curt,Wilson, Sandy J.,Lovenberg, Timothy W.,Carruthers, Nicholas I.
scheme or table, p. 903 - 907 (2009/08/15)
A novel series of imidazole containing histamine H3 receptor ligands were investigated and found to be potent functional antagonists. After improving the stability of these molecules towards liver microsomes, these compounds were found to have
Scalable synthesis of imidazole derivatives
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Page/Page column 37, (2008/06/13)
Imidazole derivatives, compositions containing them, methods of preparing them, including regioselective scale-up synthetic methods, and methods of using them.
Heterocyclic compounds
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, (2008/06/13)
Pharmaceutically useful heterocyclic compounds, compositions containing them, and methods of using them, for example, as histamine H3 receptor mediators.
