4667-80-5Relevant articles and documents
Aldehyde-selective wacker-type oxidation of unbiased alkenes enabled by a nitrite co-catalyst
Wickens, Zachary K.,Morandi, Bill,Grubbs, Robert H.
, p. 11257 - 11260 (2013)
Breaking the rules: Reversal of the high Markovnikov selectivity of Wacker-type oxidations was accomplished using a nitrite co-catalyst. Unbiased aliphatic alkenes can be oxidized with high yield and aldehyde selectivity, and several functional groups are tolerated. 18O-labeling experiments indicate that the aldehydic O atom is derived from the nitrite salt. Copyright