7065-05-6Relevant articles and documents
Design, synthesis, and evaluation of nonaqueous silylamines for efficient CO2 capture
Switzer, Jackson R.,Ethier, Amy L.,Hart, Emily C.,Flack, Kyle M.,Rumple, Amber C.,Donaldson, Jordan C.,Bembry, Ashley T.,Scott, Owen M.,Biddinger, Elizabeth J.,Talreja, Manish,Song, Myoung-Geun,Pollet, Pamela,Eckert, Charles A.,Liotta, Charles L.
, p. 299 - 307 (2014)
A series of silylated amines have been synthesized for use as reversible ionic liquids in the application of post-combustion carbon capture. We describe a molecular design process aimed at influencing industrially relevant carbon capture properties, such as viscosity, temperature of reversal, and enthalpy of regeneration, while maximizing the overall CO2-capture capacity. A strong structure-property relationship among the silylamines is demonstrated in which minor structural modifications lead to significant changes in the bulk properties of the reversible ionic liquid formed from reaction with CO 2.
Asymmetric allylic substitution by chiral palladium catalysts: Which is more reactive, major π-allyl Pd(II) species or minor π-allyl species?
Urano, Chisato,Onuki, Masatoshi,Uchida, Yuuta,Suzuki, Risa,Sato, Kiyoshi,Masui, Dai,Yamaguchi, Motowo,Yamagishi, Takamichi
, (2020/11/24)
The reactivity difference of major and minor π-allyl species was examined for two typed asymmetric allylic substitutions via linear symmetrical π-allyl and linear unsymmetrical π-allyl intermediates. 31P NMR observation of the stoichiometric re
CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
-
Page/Page column 76, (2017/01/23)
Inhibitors of HBV replication of Formula (I-A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
MACROCYCLES AS PIM INHIBITORS
-
Page/Page column 77, (2014/02/16)
The invention relates to compounds of formula (1), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of Pim kinase related conditions and diseases, preferably cancer.
The synthesis and the chemical and physical properties of non-aqueous silylamine solvents for carbon dioxide capture
Rohan, Amy L.,Switzer, Jackson R.,Flack, Kyle M.,Hart, Ryan J.,Sivaswamy, Swetha,Biddinger, Elizabeth J.,Talreja, Manish,Verma, Manjusha,Faltermeier, Sean,Nielsen, Paul T.,Pollet, Pamela,Schuette, George F.,Eckert, Charles A.,Liotta, Charles L.
, p. 2181 - 2187 (2013/01/15)
Silylamine reversible ionic liquids were designed to achieve specific physical properties in order to address effective CO2 capture. The reversible ionic liquid systems reported herein represent a class of switchable solvents where a relatively non-polar silylamine (molecular liquid) is reversibly transformed to a reversible ionic liquid (RevIL) by reaction with CO2 (chemisorption). The RevILs can further capture additional CO2 through physical absorption (physisorption). The effects of changes in structure on (1) the CO2 capture capacity (chemisorption and physisorption), (2) the viscosity of the solvent systems at partial and total conversion to the ionic liquid state, (3) the energy required for reversing the CO2 capture process, and (4) the ability to recycle the solvents systems are reported.
Aldehyde selective Wacker oxidations of phthalimide protected allylic amines: A new catalytic route to β3-amino acids
Weiner, Barbara,Baeza, Alejandro,Jerphagnon, Thomas,Feringa, Ben L.
supporting information; experimental part, p. 9473 - 9474 (2009/12/06)
(Chemical Equation Presented) A new method for the synthesis of β3-amino acids is presented. Phthalimide protected allylic amines are oxidized under Wacker conditions selectively to aldehydes using PdCl2 and CuCl or Pd(MeCN)2/s
Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide
-
Page/Page column 5; 12, (2008/12/04)
This invention relates to a method of preparation of benzofuran-2-carboxylic acid {(S)-3-methyl-1-[(4S,7R)-7-methyl-3-oxo-1-(pyridine-2-sulfonyl)-azepan-4-ylcarbamoyl]-butyl}-amide.
Nucleophilic Substitution Reactions of (Alkoxymethylene)dimethylammonium Chloride
Barrett, Anthony G. M.,Braddock, D. Christopher,James, Rachel A.,Koike, Nobuyuki,Procopiou, Panayiotis A.
, p. 6273 - 6280 (2007/10/03)
The use of imidate esters as potential replacements for diethyl azodicarboxylate and triphenylphosphine in the Mitsunobu reaction is described. A series of secondary alcohols were allowed to react with (chloromethylene)dimethylammonium chloride, generated from dimethylformamide (DMF) and oxalyl chloride, to give imidate esters. Reaction of these salts with potassium benzoate or potassium phthalimide gave the products of SN2 substitution in excellent yields with clean inversion of stereochemistry. Optimization of reaction conditions is discussed as a means to increase the atom economy of the process by minimizing the quantity of nucleophile required.
Nucleophilic substitution of (alkoxymethylene)dimethylammonium chloride with potassium phthalimide; a convenient procedure for the synthesis of imides with inversion of configuration
Barrett, Anthony G. M.,Braddock, D. Christopher,James, Rachel A.,Procopiou, Panayiotis A.
, p. 433 - 434 (2007/10/03)
Secondary alcohols are converted into their phthalimido derivatives with inversion of configuration via sequential reaction with (chloromethylene)dimethylammonium chloride and potassium phthalimide.
