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4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7,8-trimethoxy- is a complex organic compound belonging to the class of flavonoids, specifically flavones. This molecule is characterized by a benzopyran-4-one core structure, which is a type of heterocyclic compound with a benzene ring fused to a pyran ring. The compound features a hydroxyl group at the 5-position, a 3-hydroxy-4-methoxyphenyl group at the 2-position, and three methoxy groups at the 3, 7, and 8 positions. These functional groups contribute to the compound's chemical properties and potential biological activities. Flavonoids like this one are known for their antioxidant, anti-inflammatory, and anticancer properties, and they are commonly found in plants, where they play a role in pigmentation and defense mechanisms.

4670-37-5

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4670-37-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4670-37-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,7 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4670-37:
(6*4)+(5*6)+(4*7)+(3*0)+(2*3)+(1*7)=95
95 % 10 = 5
So 4670-37-5 is a valid CAS Registry Number.

4670-37-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,3'-dihydroxy-3,7,8,4'-tetramethoxyflavone

1.2 Other means of identification

Product number -
Other names Pigment II, 5,3'-Dihydroxy-3,7,8,4'-tetramethoxy-flavon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4670-37-5 SDS

4670-37-5Downstream Products

4670-37-5Relevant academic research and scientific papers

Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin

Lewin, Guy,MacIuk, Alexandre,Thoret, Sylviane,Aubert, Genevieve,Dubois, Joelle,Cresteil, Thierry

experimental part, p. 702 - 706 (2010/08/22)

Semisynthesis of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone (1), a natural flavone that binds with high affinity to tubulin, was performed from hesperidin, the very abundant Citrus flavanone, by a five-step sequence. The last step of the synthesis also gave rise to 5,3'-dihydroxy-3,6,7,4'- tetramethoxyflavone (= casticin or vitexicarpin) (10), 5,3'-dihydroxy-3,7,8,4'- tetramethoxyflavone (= gossypetin 3,7,8,4'-tetramethyl ether) (11), and, unexpectedly, 5,7,3'-trihydroxy-3,6,8,4'-tetramethoxyflavone (12) and 5,3'-dihydroxy-8-dimethylamino-3,6,7,4'-tetramethoxyflavone (= 8-dimethylaminocasticin) (13). Cytotoxicity and antitubulin activity of these five flavones, as well as 5,3'-dihydroxy-3,7,4'-trimethoxyflavone (= ayanin) (14) and intermediate 6,8-dibromo-ayanin (8), were evaluated. Comparison of the responses confirmed and clarified the influence of the A-ring substitution pattern on the biological activity.

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