467224-48-2

Basic information

• Product Name: (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester
• Synonyms: (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester
• CAS NO: 467224-48-2
• Molecular Weight: 848.174
• Mol File: 467224-48-2.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester(467224-48-2)
• EPA Substance Registry System: (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester(467224-48-2)

Safety Data

• Hazardous Substances Data: 467224-48-2(Hazardous Substances Data)

Upstream product

• 69541-82-8 N-(tert-butoxycarbonyl)valine-O-benzyl-L-threonine benzyl ester 
• 13734-41-3 t-Boc-L-valine 
• 623936-79-8 (E)-(4R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-octadec-2-enoic acid methyl ester 
• 623936-80-1 (E)-(4R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-octadec-2-en-1-ol 
• 867039-05-2 (2S,3S,4R,5R)-5-{[(tert-butyl)(dimethyl)silyl]oxy}-2,4-dimethyloctadecane-1,3-diol 
• 452956-79-5 2,2-Dimethyl-propionic acid (2R,3R)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-hexadecyl ester 
• 452956-80-8 (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-hexadecan-1-ol 
• 452956-81-9 (2S,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-hexadecanal 
• 452956-78-4 2,2-Dimethyl-propionic acid (2R,3R)-3-hydroxy-2-methyl-hexadecyl ester 
• 452956-77-3 N-(2S,3R,4'S)-(3-hydroxy-2-methylhexadecanoyl)-4'-isopropyl-3-propionyloxazolidin-2'-one 
• 350817-31-1 (2R,3R)-2-Methyl-hexadecane-1,3-diol 
• 467224-46-0 (2S,3R)-2-((4S,5S)-2,2,5-Trimethyl-[1,3]dioxan-4-yl)-hexadecan-3-ol 
• 124-25-4 myristylaldehyde 
• 867039-06-3 tert-Butyl-dimethyl-{(R)-1-[(R)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyloxy}-silane 

Downstream Products

• 867039-08-5 (3S,6S,9S,12R,13R,14R,15R)-3-Benzyloxymethyl-6-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-13-hydroxy-9-isopropyl-12,14-dimethyl-15-tridecyl-1-oxa-4,7,10-triaza-cyclopentadecane-2,5,8,11-tetraone 
• 867039-09-6 (3S,6S,9S,12R,13R)-3-Benzyloxymethyl-6-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-13-((1S,2R)-2-hydroxy-1-methyl-pentadecyl)-9-isopropyl-12-methyl-1-oxa-4,7,10-triaza-cyclotridecane-2,5,8,11-tetraone 
• 147334-89-2 Stevastelin B 
• 350817-30-0 (3S,6S,9S,12R,13R,14R,15R)-3-Benzyloxymethyl-13-hydroxy-6-((R)-1-hydroxy-ethyl)-9-isopropyl-12,14-dimethyl-15-tridecyl-1-oxa-4,7,10-triaza-cyclopentadecane-2,5,8,11-tetraone 
• 350817-36-6 (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-((1R,2R,3R)-2-hydroxy-1,3-dimethyl-4-oxo-butyl)-tetradecyl ester 
• 350817-28-6 N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-L-threonyl-O-(phenylmethyl)-L-serine (1R)-1-[(1R,2R,3R)-3-carboxy-2-hydroxy-1-methylbutyl]tetradecyl ester 
• 147334-90-5 stevastelin B3 
• 467224-49-3 N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-L-threonyl-O-(phenylmethyl)-L-serine (1R)-1-[(1R,2S,3S)-2,4-dihydroxy-1,3-dimethylbutyl]tetradecyl ester 

Relevant articles and documents

Synthetic studies on stevastelins. 1. Total synthesis of stevastelins B and B3

The synthesis of stevastelin B3 (2) and B (5) are described. In a first approach, epoxy cyclodepsipeptide 8 was considered as a promising candidate for the synthesis of the [15]-membered ring members of the stevastelins; however, the oxirane ring opening,

Total synthesis of (-)-stevastelin B

The total synthesis and an unambiguous structure confirmation of stevastelin B 1, a novel 15-membered cyclic depsipeptide, are described; the fatty acid moiety in 1, prepared stereoselectively from L-quebrachitol was converted into the amino carboxylic acid, whose macrolactamization by Shioiri's procedure effectively constructed the cyclic structure of 1.