467248-96-0Relevant academic research and scientific papers
BINOL-Salen-catalyzed highly enantioselective alkyne additions to aromatic aldehydes
Li, Zi-Bo,Pu, Lin
, p. 1065 - 1068 (2007/10/03)
(Equation presented) The BINOL-Salen compound (-)-1 can catalyze the addition of both aryl- and alkylalkynes to aromatic aldehydes at room temperature with high enantioselectivity (86-97% ee). The conditions for this catalytic process are both mild and simple. Unlike most other BINOL-based catalysts, using ligand (-)-1 not only avoids heating or cooling but also does not require the addition of Ti(OiPr)4.
Synthesis of Annulated γ-Carbolines by Palladium-Catalyzed Intramolecular Iminoannulation
Zhang, Haiming,Larock, Richard C.
, p. 3035 - 3038 (2007/10/03)
(Equation Presented) A variety of N-substituted 2-bromo-1H-indole-3-carboxaldehydes incorporating an alkyne-containing tether on the indole nitrogen have been converted to the corresponding tert-butylimines, which have been subjected to palladium-catalyze
