467253-91-4

Basic information

• Product Name: [3R(1E,3R),4R]-3-[3-cyclohexyl-3-[(3-oxapent-1-yl)oxy]propyl]-4-(t-butyldimethylsiloxy)-2-methylenecyclopentanone
• Synonyms: [3R(1E,3R),4R]-3-[3-cyclohexyl-3-[(3-oxapent-1-yl)oxy]propyl]-4-(t-butyldimethylsiloxy)-2-methylenecyclopentanone
• CAS NO: 467253-91-4
• Molecular Weight: 438.723
• Mol File: 467253-91-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3R(1E,3R),4R]-3-[3-cyclohexyl-3-[(3-oxapent-1-yl)oxy]propyl]-4-(t-butyldimethylsiloxy)-2-methylenecyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: [3R(1E,3R),4R]-3-[3-cyclohexyl-3-[(3-oxapent-1-yl)oxy]propyl]-4-(t-butyldimethylsiloxy)-2-methylenecyclopentanone(467253-91-4)
• EPA Substance Registry System: [3R(1E,3R),4R]-3-[3-cyclohexyl-3-[(3-oxapent-1-yl)oxy]propyl]-4-(t-butyldimethylsiloxy)-2-methylenecyclopentanone(467253-91-4)

Safety Data

• Hazardous Substances Data: 467253-91-4(Hazardous Substances Data)

Upstream product

• 117254-07-6 (4R)-2-(N,N-diethylamino)methyl-4-(t-butyldimethylsiloxy)-cyclopent-2-en-1-ol 
• 467253-90-3 (1R)-3-chloro-1-cyclohexylprop-1-yl 1-ethoxyethyl ether 

Downstream Products

• 263381-45-9 [3R(1E,3R),4R]-3-(3-cyclohexyl-3-hydroxypropyl)-4-(t-butyldimethylsiloxy)-2-methylenecyclopentanone 

Relevant articles and documents

3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.

A series of prostaglandin DP agonists containing a 3-oxa-15-cyclohexyl motif was synthesized and evaluated in several in vitro and in vivo biological assays. The reference compound ZK 118.182 (9beta-chloro-15-cyclohexyl-3-oxa-omega-pentanor PGF(2alpha)) i