467427-84-5 Usage
Uses
Used in Pharmaceutical Industry:
2,7-Dimethyl-2,3-dihydrobenzofuran-6-carboxylic acid is used as a precursor in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drug candidates and bioactive molecules. Its unique structure allows for the creation of compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,7-Dimethyl-2,3-dihydrobenzofuran-6-carboxylic acid serves as a starting material for the synthesis of agrochemicals, leveraging its structural properties to produce compounds that can be used in crop protection and other agricultural applications.
Used in Medicinal Chemistry:
2,7-Dimethyl-2,3-dihydrobenzofuran-6-carboxylic acid is utilized as a key intermediate in medicinal chemistry for the production of cyclic compounds and natural product synthesis, playing a crucial role in the discovery and development of novel therapeutic agents.
Used in Organic Synthesis:
As an important chemical in organic synthesis, 2,7-Dimethyl-2,3-dihydrobenzofuran-6-carboxylic acid is employed as a versatile building block for the creation of a wide range of organic compounds, contributing to the advancement of chemical research and the development of new materials.
Check Digit Verification of cas no
The CAS Registry Mumber 467427-84-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,7,4,2 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 467427-84:
(8*4)+(7*6)+(6*7)+(5*4)+(4*2)+(3*7)+(2*8)+(1*4)=185
185 % 10 = 5
So 467427-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O3/c1-6-5-8-3-4-9(11(12)13)7(2)10(8)14-6/h3-4,6H,5H2,1-2H3,(H,12,13)
467427-84-5Relevant academic research and scientific papers
Li, Renhe,Dong, Guangbin
, p. 1697 - 1701 (2018)
Herein we report a direct annulation between aryl iodides and epoxides through palladium/norbornene (Pd/NBE) cooperative catalysis. An iso-propyl ester substituted NBE was found to be most efficient to suppress the formation of multiple-NBE-insertion byproducts and affords the desired 2,3-dihydrobenzofuran derivatives in 44–99 % yields. The reaction is scalable and tolerates a range of functional groups. Asymmetric synthesis is realized using an enantiopure epoxide. Application of this method into a concise synthesis of insecticide fufenozide is demonstrated.
