468078-24-2Relevant academic research and scientific papers
Preparation of 3,4-enynoindoles via directed lithiation and application to the synthesis of 3,4-carbocycloindoles
Pérez-Serrano, Leticia,Casarrubios, Luis,Domínguez, Gema,Freire, Guillermo,Pérez-Castells, Javier
, p. 5407 - 5415 (2002)
Lithiation at C4 of the indole nucleus is readily directed by several functional groups. The 4-substituted indoles thus obtained are transformed into suitable substrates for metathesis reactions. Ring-closing metathesis effected on these compounds lead to skeletons related to several indole alkaloids.
