4683-50-5

Basic information

• Product Name: 3-METHOXY-2-CYCLOPENTEN-1-ONE
• Synonyms: 3-METHOXY-2-CYCLOPENTEN-1-ONE;3-Methoxycyclopent-2-enone;3-Methoxy-2-cyclopenten-1-one 99%
• CAS NO: 4683-50-5
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.13
• Product Categories: C3 to C6;Carbonyl Compounds;Ketones
• Mol File: 4683-50-5.mol
• Article Data: 15

Chemical Properties

• Melting Point: 49-53 °C(lit.)
• Boiling Point: 214.9 °C at 760 mmHg
• Flash Point: 96.5 °C
• Appearance: /
• Density: 1.06 g/cm³
• Vapor Pressure: 0.152mmHg at 25°C
• Refractive Index: 1.466
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 3-METHOXY-2-CYCLOPENTEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-2-CYCLOPENTEN-1-ONE(4683-50-5)
• EPA Substance Registry System: 3-METHOXY-2-CYCLOPENTEN-1-ONE(4683-50-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4683-50-5(Hazardous Substances Data)

Usage

Uses

3-Methoxy-2-cyclopenten-1-one (3-methoxycyclopent-2-enone) may be used in the following studies:Synthesis of 3-cyclopentyl-2-cyclopenten-1-one.As a starting material in the synthesis of 3-alkyl-2-aryl-2-cyclopenten-1-one oxime derivatives and kjellmanianone, an antibiotic.As one of the reagent in the synthesis of 3-aryl enones.Preparation of 1:1 diastereomeric mixture of TBS (tert-butyldimethylsilyl)-protected enones.

General Description

3-Methoxy-2-cyclopenten-1-one (3-methoxycyclopent-2-enone) is a 3-methoxycycloalk-2- enone.

InChI:InChI=1/C6H8O2/c1-8-6-3-2-5(7)4-6/h4H,2-3H2,1H3

Upstream product

• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 3859-41-4 1,3-cyclopentadione 
• 77-78-1 dimethyl sulfate 
• 542-92-7 cyclopenta-1,3-diene 
• 930-60-9 maleic anhydride 
• 67-56-1 methanol 
• 53102-14-0 3-chlorocyclopent-2-en-1-one 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 

Downstream Products

• 114423-89-1 3-methoxy-5-propyl-2-cyclopentenone 
• 141693-19-8 methyl (+/-)-4-methoxy-2-oxo-3-cyclopentene-1-carboxylate 
• 6621-70-1 methyl ether of γ-tropolone 
• 296764-08-4 3-[2,4-Bis(methoxymethoxy)phenyl]-2-cyclopenten-1-one 
• 1118944-98-1 5-(1-buten-4-yl)-3-methoxy-2-cyclopenten-1-one 
• 1118944-94-7 5-(2-chlorobenzyl)-3-methoxy-2-cyclopenten-1-one 

Relevant articles and documents

Catalyst-controlled regiodivergent vinylogous aza-Morita–Baylis–Hillman reactions

Regiodivergent vinylogous aza-Morita–Baylis–Hillman reactions of 3-vinylcyclopent-2-en-1-one 1 were developed in a catalyst-controlled manner. While treatment of 1 with N-tosylarylaldimines 2 in the presence of DABCO gave the α-adducts as the sole regiois

Ionic liquid supported on magnetic nanoparticles as highly efficient and recyclable catalyst for the synthesis of β-keto enol ethers

A magnetically ionic liquid supported on γ-Fe2O 3 nanocatalyst (AlxCly-IL-SiO 2γ-Fe2O3) was synthesized and evaluated as a recoverable catalyst for the synthesis of β-keto enol ethers. The immobilized catalyst proved to be effective and provided the products in high to excellent yield at room temperature. Moreover, the catalyst could be easily recovered by magnetic separation and recycled for six times without significant loss of its catalytic activity.

Asymmetric synthesis of O-protected acyloins using enoate reductases: Stereochemical control through protecting group modification

O-Protected cyclic acyloins were obtained in nonracemic form through asymmetric bioreduction of α,β-unsaturated alkoxy ketones by using 11 different enoate reductases from the "Old Yellow Enzyme" family. The stereochemical outcome of the biotransformation could be switched by variation of the O-protecting group or by the ring size of the substrate, which allows access to both stereoisomers in up to >97 % ee Whereas α-alkoxy enones were readily accepted as substrates, β-analogs were not converted. Overall, α-alkoxy enones represent a novel type of substrate for flavin-dependent ene-reductases. Copyright