468737-07-7

Upstream product

• 162544-16-3 (E)-3-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-pyridin-4-yl-acrylic acid ethyl ester 
• 67387-76-2 3-cyclopentyloxy-4-methoxybenzylaldehyde 
• 137-43-9 Cyclopentyl bromide 
• 199331-21-0 (E)-3-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-pyridin-4-yl-acrylic acid 

Downstream Products

• 170985-18-9 (E)-3-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-2-pyridin-4-yl-propenone 
• 468737-13-5 (2R,3R)-3-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-3-phenyl-2-pyridin-4-yl-propan-1-one 
• 468737-15-7 (2R,3R)-3-(3-Cyclopentyloxy-4-methoxy-phenyl)-3-phenyl-2-pyridin-4-yl-thiopropionic acid S-propyl ester 
• 162542-90-7 R-(+)-4-(2-(3-cyclopentyloxy-4-methoxyphenyl)-2-phenylethyl)pyridine 

Relevant academic research and scientific papers

CDP840. A prototype of a novel class of orally active anti-inflammatory phosphodiesterase 4 inhibitors

The discovery, synthesis and biological activity of a series of triarylethane phosphodiesterase 4 inhibitors is described. Structure-activity relationship studies are presented for CDP840 (29), a potent, chiral, selective inhibitor of PDE 4 (IC50/su