468773-24-2

Basic information

• Product Name: (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester
• Synonyms: (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester
• CAS NO: 468773-24-2
• Molecular Weight: 414.48
• Mol File: 468773-24-2.mol

Chemical Properties

• CAS DataBase Reference: (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester(468773-24-2)
• EPA Substance Registry System: (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester(468773-24-2)

Safety Data

• Hazardous Substances Data: 468773-24-2(Hazardous Substances Data)

Upstream product

• 5162-44-7 1-bromo-4-butene 
• 468773-25-3 (3S)-3-[(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester 
• 440321-02-8 (S)-tert-butyl 3-amino-4-hydroxybutanoate 
• 133565-45-4 (S)-tert-butyl 3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-hydroxybutanoate 

Downstream Products

• 468773-43-5 [8-methyl-3-(2-nitrobenzenesulfonyl)-7-oxa-3,8-diazabicyclo[4.2.1]non-2-yl]acetic acid tert-butyl ester 
• 468773-33-3 (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-oxobutyric acid tert-butyl ester 

Relevant articles and documents

Amino acid derived intramolecular 1,3-dipolar cycloadditions that form bridged medium ring systems with diastereoselective control

Intramolecular nitrone cycloadditions using amino acid precursors, generate aminohydroxyazepine and amino hydroxypiperidine templates. The cycloaddition reactions yield either a [4.3.0] fused system or in most cases a [4.2.1] bridged system. The [4.2.1] bridged system allows for the stereospecific preparation of 3-amino-5-hydroxyazepines while the [4.3.0] system allows for the preparation of 3-amino-5-hydroxymethyl piperidines.