46882-99-9Relevant academic research and scientific papers
Ligand-free copper-catalyzed synthesis of substituted benzimidazoles, 2-aminobenzimidazoles, 2-aminobenzothiazoles, and benzoxazoles
Saha, Prasenjit,Ramana, Tamminana,Purkait, Nibadita,Ali, Md. Ashif,Paul, Rajesh,Punniyamurthy, Tharmalingam
supporting information; experimental part, p. 8719 - 8725 (2010/02/28)
(Chemical Equation Presented) The synthesis of substituted benzimidazoles, 2-aminobenzimidazoles, 2-aminobenzothiazoles, and benzoxazoles is described via intramolecular cyclization of o-bromoaryl derivatives using copper(II) oxide nanoparticles in DMSO under air. The procedure is experimentally simple, general, efficient, and free from addition of external chelating ligands. It is a heterogeneous process and the copper(II) oxide nanoparticles can be recovered and recycled without loss of activity. 2009 American Chemical Society.
Design and synthesis of 3-(benzimidazol-2-yl)-propionic acids as thromboxane A2 receptor antagonists
Garuti,Ghedini,Leoni,Baraldi,Dionisotti
, p. 1531 - 1546 (2007/10/02)
A series of 3-(benzimidazol-2-yl)-propionic acids substituted at the N1 nitrogen with methyl and benzyl groups and at the C5 and C6 positions with chloro, methoxy, amino, hydroxyl groups were synthesized and tested as TXA2 receptor antagonists.
