4698-94-6

Usage

Uses

Used in Pharmaceutical Industry:
(2S)-3-(3-fluorophenoxy)-1,2-epoxypropane is used as an intermediate in the synthesis of pharmaceutical compounds for its unique chemical structure and reactivity.
Used in Chemical Research:
(2S)-3-(3-fluorophenoxy)-1,2-epoxypropane is used as a research compound to study the properties and reactions of epoxides and their derivatives, as well as their potential applications in various fields.
Used in Industrial Applications:
(2S)-3-(3-fluorophenoxy)-1,2-epoxypropane may be used in the development of new materials, coatings, or adhesives due to its unique chemical structure and properties.

Upstream product

• 372-20-3 3-fluorophenol 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 106-89-8 epichlorohydrin 

Downstream Products

• 140662-33-5 (4-{2-[3-(3-Fluoro-phenoxy)-2-hydroxy-propylamino]-ethoxy}-phenoxy)-acetic acid methyl ester 
• 1224936-58-6 C₁₈H₂₀FNO₂ 
• 1254940-25-4 C₂₆H₂₇FN₄O₂S 
• 1224936-48-4 C₁₅H₂₂FNO₃ 
• 5741-42-4 3-<3-Fluor-phenoxy>-1-isopropylamino-propanol-(2) 

Relevant academic research and scientific papers

Thienopyrimidines as β3-adrenoceptor agonists: Hit-to-lead optimization

Resulting from a vHTS based on a pharmacophore alignment on known β3-adrenoceptor ligands, an aryloxypropanolamine scaffold comprising a thienopyrimidine moiety was further optimized as a human β3-AR agonist, yielding a lead compound with an excellent cellular activity of EC50 = 20 pM, selectivity over hβ1- and hβ2-adrenoceptors and a promising safety profile.

ANALGESIC THAT BINDS FILAMIN A

A compound, composition and method are disclosed that can provide analgesia. A contemplated compound has a structure that corresponds to Formula A, wherein A, B, X, R1, R2, R7 and R8, and the dashed lines are defined within.

Method of using calcilytic compounds

The present invention features calcilytic compounds. "Calcilytic compounds" refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.

Thiazolidine and oxazolidine derivatives, their preparation and their medical use

Compounds of formula (I): STR1 and salts, esters and solyates thereof and pro-drugs therefor are useful for the treatment and/or prophylaxis of a variety of disorders, including one or more of: hyperlipemia, hyperglycemia, obesity, glucose tolerance insufficiency, insulin resistance and diabetic complications.

Studies on new phosphodiesterase inhibitors. I. Synthesis of 1-(2,3-epoxypropoxy)-2(4)-fluorobenzenes and 1-(2-hydroxy-3-morpholinopropoxy and piperazino)fluorobenzene derivatives

A series of 1-(2,3-epoxypropoxy)-2(4)-fluorobenzenes and their corresponding 1-(2-hydroxy-3-morpholino propoxy and piperazino)fluorobenzene derivatives (8a-f) were synthesised via a short synthetic route in good chemical yields and were evaluated for inot