4705-37-7Relevant academic research and scientific papers
General and highly active catalyst for mono and double Hiyama coupling reactions of unreactive aryl chlorides in water
Lee, Dong-Hwan,Jung, Ji-Young,Jin, Myung-Jong
supporting information; experimental part, p. 9046 - 9048 (2011/02/17)
A new β-diketiminatophosphane Pd catalyst was found to be highly effective in the mono and double Hiyama coupling reactions of unactivated aryl chlorides in water.
Studies of microwave-enhanced Suzuki-Miyaura vinylation of electron-rich sterically hindered substrates utilizing potassium vinyltrifluoroborate
Brooker, Matthew D.,Cooper Jr., Stefan M.,Hodges, Dena R.,Carter, Rhiannon R.,Wyatt, Justin K.
experimental part, p. 6748 - 6752 (2011/02/25)
The Suzuki-Miyaura cross-coupling of sterically hindered and electron-rich ortho,ortho′-substituted aryl halides with potassium vinyltrifluoroborate utilizing microwave irradiation has been conducted while adjusting solvent ratio, irradiation time, and catalyst loading to find optimal conditions. Coupling of benzyl 3,5-bis(benzyloxy)-4-bromobenzoate leads to a mixture of the desired styrene derivative and the reduced product. 4-Bromo-1,3,5- trimethoxybenzene, methyl 4-bromo-3,5-dimethoxybenzoate, and mesitylene bromide were also coupled to test the breadth and scope of this methodology. Of these substrates tested only 4-bromo-1,3,5-trimethoxybenzene was not vinylated successfully, which is believed to be due to the electron-rich nature of this system.
