470664-40-5Relevant academic research and scientific papers
Photoactivatable synthetic Ras proteins: "Baits" for the identification of plasma-membrane-bound binding partners of Ras
Kuhlmann, Juergen,Tebbe, Andreas,Voelkert, Martin,Wagner, Melanie,Uwai, Koji,Waldmann, Herbert
, p. 2546 - 2550 (2002)
The combination of organic synthesis with cell biology provides access to a chimera of the signal-transducing Ras protein, which contains a photoactivatable benzophenone group in its isoprenoid membrane anchor, yet retains biological activity. The semisyn
Synthesis and Biological Activity of Photoactivatable N-Ras Peptides and Proteins
Voelkert, Martin,Uwai, Koji,Tebbe, Andreas,Popkirova, Boriana,Wagner, Melanie,Kuhlmann, Juergen,Waldman, Herbert
, p. 12749 - 12758 (2007/10/03)
A modular strategy for the assembly of farnesylated N-Ras heptapeptides carrying a photoactivatable benzophenone (BP) group within the lipid residue is described. This strategy is based on the fragment condensation of a N-terminal hexapeptide synthesized
