471-56-7

Basic information

• Product Name: 3-(2-acetyl-2,4b,6a,9,9,10b,12a-heptamethyloctadecahydrochrysen-1-yl)propanoic acid
• CAS NO: 471-56-7
• Molecular Formula: C₃₀H₅₀O₃
• Molecular Weight: 458.7162
• Mol File: 471-56-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 536.8°C at 760 mmHg
• Flash Point: 292.5°C
• Density: 1.001g/cm³
• Vapor Pressure: 5.97E-13mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: 3-(2-acetyl-2,4b,6a,9,9,10b,12a-heptamethyloctadecahydrochrysen-1-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-acetyl-2,4b,6a,9,9,10b,12a-heptamethyloctadecahydrochrysen-1-yl)propanoic acid(471-56-7)
• EPA Substance Registry System: 3-(2-acetyl-2,4b,6a,9,9,10b,12a-heptamethyloctadecahydrochrysen-1-yl)propanoic acid(471-56-7)

Safety Data

• Hazardous Substances Data: 471-56-7(Hazardous Substances Data)

Upstream product

• 559-74-0 friedelin 
• 64-19-7 acetic acid 
• 113376-12-8 4α-hydroxyfriedelan-3-one 
• 29621-75-8 3,4-secofriedelan-3 <*> 4-olide 
• 113376-15-1 friedel-3-en-3-yl benzoate 
• 161739-60-2 3-trimethylsiloxyfriedel-3-ene 
• 287110-78-5 3-[(1S,2S,4aS,4bR,6aR,10aR,10bS,12aR)-2-((R)-1-Hydroxy-ethyl)-2,4b,6a,9,9,10b,12a-heptamethyl-octadecahydro-chrysen-1-yl]-propionic acid 

Downstream Products

• 29621-75-8 3,4-secofriedelan-3 <*> 4-olide 
• 6938-93-8 A-nor-friedelene-⁽²⁾ 

Relevant articles and documents

Hemisynthetic secofriedelane triterpenes with inhibitory activity against the growth of human tumor cell lines in vitro

Seco acids 7 and 9 and hydroxylated analogues 5 and 6 derived from friedelane triterpenes were synthesized stereoselectively in high yields. Compounds 5-9 were evaluated for their ability to inhibit in vitro the growth of three human tumor cell lines, MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer), and SF-268 (CNS cancer). Only compounds 7 and 9 were found to possess significant growth inhibitory effects, exhibiting GI 50 values that range from 24.6 to 32.8 μM and 10.9 to 17.6 μM, respectively.

Basic Autoxidation of Friedelin

Base-catalized autoxidation of a triterpene ketone, friedelin, in the presence of potassium t-butoxide gave four products, and their structures and formation mechanism were investigated.The common intermediate to these compounds was suggested to be 4-hydroperoxyfriedelan-3-one, not friedelane-2,3-dione. 3-Oxafriedel-1-ene-2-carboxylic acid was a dehydration product of the main product, 2-hydroxy-3-oxafriedelane-2-carboxylic acid.