4710-95-6

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-2-deoxy-D-allopyranose hydrochloride is used as a component in drug development for its potential therapeutic properties and as a chemical intermediate in organic synthesis to facilitate the creation of new pharmaceutical compounds.
Used in Biochemical Research:
2-Amino-2-deoxy-D-allopyranose hydrochloride is used as a biochemical research tool to study the structure, function, and interactions of amino sugars in biological systems.
It is important to handle and store 2-Amino-2-deoxy-D-allopyranose hydrochloride according to the safety guidelines provided by the manufacturer, as it can be toxic if ingested or inhaled and may cause irritation to the skin and eyes.

Upstream product

• 103782-08-7 allosamidin 
• 887472-18-6 N-benzyl-D-tagatosylamine 
• 41847-61-4 (3S,4S,5R)-2-(hydroxymethyl)tetrahydropyran-2,3,4,5-tetrol 

Downstream Products

• 29086-03-1 2-deoxy-2-(bromoacetamido)-D-mannose 
• 98-98-6 2-Picolinic acid 
• 16932-62-0 D-mannosaminic acid 
• 1198593-82-6 (4S,5S)-5-hydroxy-1-phenyl-4-(D-arabino-tetritol-1-yl)imidazolidine-2-selone 
• 66395-17-3 1-methyl-1-nitroso-3-(2-deoxy-D-galactos-2-yl)urea 
• 31505-45-0 2-((3R,4R,5R,6R)-2,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-isoindole-1,3-dione 
• 81176-80-9 D-galactosaminic acid 
• 882503-87-9 2-[(E)-cinnamylidene]amino-2-deoxy-D-galactopyranose 

Relevant academic research and scientific papers

Synthesis of N-protected galactosamine building blocks from D-tagatose via the heyns rearrangement

N-Acetyl-D-galactosamine (11), a very important naturally occurring building block of oligosaccharides, is easily accessible via the Heyns rearrangement of D-tagatose (3) with benzylamine. The short and efficient synthesis of various differently N-protected D-galactosamine derivatives is reported. Copyright Taylor & Francis Group, LLC.

THE STRUCTURE OF ALLOSAMIDIN, A NOVEL INSECT CHITINASE INHIBITOR, PRODUCED BY STREPTOMYCES SP.

Allosamidin (1), a novel insect chitinase inhibitor, was isolated from the mycelium of Streptomyces sp. and characterized as 1, which was a basic pseudotrisaccharide consisting of 2-acetamido-2-deoxy-D-allose (N-acetyl-D-allosamine) and a novel aminocyclitol derivative(3), termed allosamizoline.

Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals

O-acetylated glycals react with ceric ammonium nitrate in the presence of sodium azide to provide, in good yield, O-acetylated 2-azido-2-deoxy glycosyl nitrates. These nitrates can be used to prepare 2-amino-2-deoxy sugars, such as D-galactosamine and lactosamine. The O-acetylated 2-azido-2-deoxy glycosyl nitrates can alternately be converted to O-acetylated 2-azido-2-deoxy glycosyl halides which are useful in the preparation of O-acetylated 2-azido-2-deoxy glycosides, which in turn can be reduced to 2-amino-2-deoxy glycosides. Of particular interest are the syntheses of 2-amino-2-deoxy glycosides which correspond to the terminal units of the antigenic determinant for the human A blood group. Attachment of these glycosides to a solid support provides immunoabsorbents which efficiently and preferentially absorb anti-A antibodies from blood plasma.