4714-36-7

Basic information

• Product Name: 1-nitro-4-(trichloroethenyl)benzene
• CAS NO: 4714-36-7
• Molecular Formula: C₈H₄Cl₃NO₂
• Molecular Weight: 252.4819
• Mol File: 4714-36-7.mol

Chemical Properties

• Boiling Point: 297.7°C at 760 mmHg
• Flash Point: 133.8°C
• Density: 1.548g/cm³
• Vapor Pressure: 0.00236mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: 1-nitro-4-(trichloroethenyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-nitro-4-(trichloroethenyl)benzene(4714-36-7)
• EPA Substance Registry System: 1-nitro-4-(trichloroethenyl)benzene(4714-36-7)

Safety Data

• Hazardous Substances Data: 4714-36-7(Hazardous Substances Data)

Usage

Type of compound

Nitroaromatic compound

Substituents

Nitro group and trichloroethenyl group attached to a benzene ring

Physical state

Yellow solid

Solubility

Insoluble in water, soluble in organic solvents

Uses

Intermediate in the synthesis of other organic compounds, precursor in the production of dyes and pigments, pesticide and insecticide (although use has declined due to environmental and health concerns)

Hazard classification

Hazardous chemical, requires careful handling to minimize exposure.

Upstream product

• 700-60-7 trichlorovinylbenzene 
• 4714-32-3 1-nitro-4-(1,2,2,2-tetrachloro-ethyl)-benzene 
• 100-01-6 4-nitro-aniline 
• 75867-38-8 4-nitro-1-(trimethylsilylethynyl)benzene 
• 100-05-0 4-nitrobenzenediazonium chloride 
• 2201-11-8 1,1,1-trichloro-2-(4-nitrophenyl)-ethane 

Downstream Products

• 63630-18-2 4(trichloroethenyl) o-nitroaniline 
• 63630-19-3 2-Nitro-4-(trichlorethenyl)benzoesulfonsaeureamid 
• 60200-06-8 4-amino-6-trichlorovinyl-1,3-benzenedisulfonamide 
• 60285-85-0 4-amino-6-(trichlorovinyl)benzene-1,3-disulfonyl dichloride 
• 63630-20-6 2-Amino-4-(trichlorethenyl)benzolsulfonamid 
• 63630-17-1 4-(Trichlorethenyl)anilin 

Relevant articles and documents

A study on reactions of an alkynylsilane with oxone-KX (X = Cl, Br, I) and its one-pot transformation into an amide/ester

Oxyhalogenation reactions of a variety of alkynylsilanes were studied using oxone as mild oxidant and KCl, KBr, and KI as halogen sources. In this study, reaction of an alkynylsilane with oxone-KX (X = Cl or Br) produced trichloromethyl/tribromomethyl ketones inhigh yields. Under similar conditions, however, reactions of alkynylsilanes with oxone-KI were found to give exclusively 1,2,2-triiodovinyl derivatives in high yields. In this study, new methods were deveoped for effcient one-pot tranformation of alkynylsilanes into amides and esters by reaction with amines and alcohols respectively via trihalomethyl ketone.

THIOCYANATO-, BROMO-, AND CHLOROARYLATION OF TRICHLOROETHYLENE

By reactions of arenediazonium salts with trichloroethylene in aqueous acetone in the presence of alkali metal thiocyanates, bromides, or chlorides, catalyzed by Cu(II) or Fe(II) salts, we synthesized 1-thiocyanato(bromo, chloro)-1,2,2-trichloro-2-arylethanes.These were treated with alcoholic potassium hydroxide to give α,β,β-trichlorostyrenes.Trichloroethylene is less reactive in the anionarylation than vinylidene and vinyl chlorides.

4-Amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide, a new, potent fasciolicide

The synthesis and fasciolicidal activity of 4-amino-6-(trichloroethenyl)-1,3- benzenedisulfonamide are reported. A single dose of 15 mg/kg was effective in removing over 90% of immature Fasciola hepatica from sheep (6 weeks after infection) and calves (8 weeks after infection). A 2.5 mg/kg dose removed over 90% of mature (16 weeks old) liver fluke from sheep. Single oral doses up to 400 mg/kg were tolerated by sheep without gross toxic symptoms.