47173-34-2

Upstream product

• 28863-60-7 N-(5-benzoylamino-[1,3,4]thiadiazol-2-yl)-N-phenyl-acetamide 
• 98-88-4 benzoyl chloride 
• 21123-44-4 2-Amino-5-phenylamino-1,3,4-thiadiazole 
• 29030-03-3 N-(3-benzoyl-thioureido)-N'-phenyl-guanidine; toluene-4-sulfonate 
• 109853-19-2 C₁₅H₁₄N₄OS₂ 
• 28863-51-6 N-(3-benzoyl-thioureido)-N'-phenyl-guanidine; nitrate 

Downstream Products

• 28863-60-7 N-(5-benzoylamino-[1,3,4]thiadiazol-2-yl)-N-phenyl-acetamide 
• 28938-50-3 N-(5-anilino-[1,3,4]thiadiazol-2-yl)-benzimidic acid methyl ester 

Relevant academic research and scientific papers

1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS

The present invention presents novel 1,3,4-thiadiazole derivatives of formula I which have useful antiviral activity against herpes virus, cytomegalovirus (CMV).

A new route to 1,2,4-triazoles and 1,3,4-thiadiazoles from 1-acylbithiourea

The intramolecular cyclization of 1-acylbithiourea 1 gave 1,2,4-triazole 2 and 1,3,4-thiadiazole 3. The reaction of 1 with p-toluenesulfonyl chloride in the presence of triethylamine afforded 3. Treatment of 1 with methyl iodide in the absence of any base yielded 2-methylthio-1,3,4-thiadiazole 10 and 2-imino-1,3,4-thiadiazoline 12.