471907-67-2Relevant academic research and scientific papers
Chemoenzymatic stereoconvergent synthesis of 3-O-benzoyl azidosphingosine
Compostella, Federica,Franchini, Laura,Giovenzana, Giovanni Battista,Panza, Luigi,Prosperi, Davide,Ronchetti, Fiamma
, p. 867 - 872 (2007/10/03)
The synthesis of 3-O-benzoyl azidosphingosine 1 through a stereoconvergent approach is described. Nucleophilic addition of the Grignard reagent of 1-pentadecyne to cyclohexylidene-D-glyceraldehyde results in a mixture of diastereoisomeric propargylic alco
3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists.
Yuan, Jun,Gulianello, Michael,De Lombaert, Stephane,Brodbeck, Robbin,Kieltyka, Andrzej,Hodgetts, Kevin J
, p. 2133 - 2136 (2007/10/03)
The synthesis of a series of 3-aryl pyrazolo[4,3-d]pyrimidines as potential corticotropin-releasing factor (CRF-1) antagonists is described. The effects of substitution on the aromatic ring, the amino group and the pyrazolo ring on CRF-1 receptor binding
