472804-18-5

Upstream product

• 648889-07-0 2-(2,4-dichloro-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 2447-79-2 2,4-dichlorobenzamide 
• 2775-38-4 2,4-dichlorothiobenzamide 

Downstream Products

• 478370-90-0 3-{4-Methoxy-3-[({[4-methyl-2-(2,4-dichlorophenyl)-1,3-thiazol-5-yl]carbonyl}amino)methyl]-phenyl}-6-methoxybenzoic acid 
• 478370-65-9 3-{4-Methoxy-3-[({[4-methyl-2-(2,4-dichlorophenyl)-1,3-thiazol-5-yl]carbonyl}amino)methyl]phenyl}benzoic acid 

Relevant academic research and scientific papers

Synthesis, Activity, and Docking Study of Novel Phenylthiazole-Carboxamido Acid Derivatives as FFA2 Agonists

Free fatty acid receptor 2 (FFA2), also known as GPR43, is activated by short-chain fatty acids (SCFAs) that are mainly produced by the gut microbiota through the fermentation of undigested carbohydrates and dietary fibers. FFA2 currently appears to be a

ARYL PIPERIDINE DERIVATIVES AND USE THEREOF TO REDUCE ELEVATED LEVELS OF LDL-CHOLESTEROL

This invention relates to novel compounds which up-regulate LDL receptor (LDL-r) expression and to processes for their preparation, pharmaceutical compositions containing them and their medical use. More particularly, this invention relates to novel aromatic piperidines and their use in therapy.