472979-60-5

Upstream product

• 58931-16-1 (R)-1-benzyloxypent-4-en-2-ol 
• 74-88-4 methyl iodide 
• 60656-87-3 benzyloxyacetoaldehyde 

Downstream Products

• 1196458-31-7 (3R)-4-benzyloxy-3-methoxybutan-1-ol 
• 472979-11-6 (2S,3'R)-2-(4'-benzyloxy-3'-methoxy-butyrylamino)-3-hydroxy-propionic acid methyl ester 
• 472979-16-1 (2'R)-2-(3'-benzyloxy-2'-methoxy-propyl)-oxazole-4-carboxylic acid methyl ester 
• 472979-05-8 (3R)-4-benzyloxy-3-methoxy-butanic acid 
• 472979-65-0 (3R)-4-benzyloxy-3-methoxy-butyraldehyde 

Relevant academic research and scientific papers

Total synthesis of bongkrekic acid via sequential suzuki-miyaura coupling reactions

An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments. Georg Thieme Verlag Stuttgart.

Toward the total synthesis of disorazole A(1) and C(1): asymmetric synthesis of a masked southern segment.

[reaction: see text] A highly convergent asymmetric synthesis of the masked southern segment of the antimitotic agent disorazole A(1) involves a Sonogashira coupling between a C1'-C10' enyne and a suitably protected C11'-C19' vinyl iodide. The central E,Z,Z-triene moiety is masked as a more stable ynediene.