473-73-4

Usage

Uses

Used in Organic Synthesis:
3-(carboxymethyl)-2,2-dimethylcyclobutanecarboxylic acid serves as a versatile building block in organic synthesis, leveraging its acid and alkyl functionalities to form a variety of complex molecular structures. Its unique ring structure and substituents make it a promising candidate for the creation of novel compounds with tailored properties.
Used in Drug Design:
In the pharmaceutical industry, 3-(carboxymethyl)-2,2-dimethylcyclobutanecarboxylic acid is utilized as a key intermediate in drug design. Its structural features allow for the development of new pharmaceutical agents with potential applications in treating various diseases. 3-(carboxymethyl)-2,2-dimethylcyclobutanecarboxylic acid's ability to be modified and functionalized makes it an attractive scaffold for medicinal chemists to optimize the properties of drug candidates.
Further research and analysis are required to fully explore the chemical properties and potential applications of 3-(carboxymethyl)-2,2-dimethylcyclobutanecarboxylic acid, ensuring its place in the advancement of organic chemistry and drug development.

Upstream product

• 127-91-3 (1R,5R)-(+)-β-pinene 
• 80-56-8 Pinene 
• 7785-70-8 (+)-α-pinene 
• 2009-00-9 sabinene 

Relevant academic research and scientific papers

An analytical approach for a comprehensive study of organic aerosols

Unknown products identified precisely: The coupling of liquid chromatography to NMR spectroscopy, mass spectrometry, and infrared spectroscopy and the use of high-resolution mass spectrometry is utilized to investigate the formation of atmospheric-relevan

Carboxylic acids in secondary aerosols from oxidation of cyclic monoterpenes by ozone

A series of smog chamber experiments have been conducted in which five cyclic monoterpenes were oxidized by ozone. The evolved secondary aerosol was analyzed by GC-MS and HPLC-MS for nonvolatile polar oxidation products with emphasis on the identification of carboxylic acids. Three classes of compounds were determined at concentration levels corresponding to low percentage molar yields: i.e. dicarboxylic acids, oxocarboxylic acids, and hydroxyketocarboxylic acids. Carboxylic acids are highly polar and have lower vapor pressures than their corresponding aldehydes and may thus play an important role in secondary organic aerosol formation processes. The most abundant carboxylic acids were the following: cis-pinic acid AB1 (cis-3- carboxy-2,2-dimethylcyclobutylethanoic acid) from α-and β-pinene; cis- pinonic acid A3 (cis-3-acetyl-2,2-dimethylcyclobutylethanoic acid) and cis- 10-hydroxypinonic acid AB6 (cis-2,2-dimethyl-3- hydroxyacetylcyclobutylethanoic acid) from α-pinene and β-pinene; cis-3- caric acid C1 (cis-2,2-dimethyl-1,3-cyclopropyldiethanoic acid), cis-3- caronic acid C3 (2,2-dimethyl-3-(2-oxopropyl)cyclopropanylethanoic acid), and cis-10-hydroxy-3-caronic acid C6 (cis-2,2-dimethyl-3-(hydroxy-2- oxopropyl)cyclopropanylethanoic acid) from 3-carene; cis-sabinic acid S1 (cis-2-carboxy-1-isopropylcyclopropylethanoic acid) from sabinene; limonic acid L1 (3-isopropenylhexanedioic acid), limononic acid L3 (3-isopropenyl-6- oxo-heptanoic acid), 7-hydroxylimononic acid L6 (3-isopropenyl-7-hydroxy-6- oxoheptanoic acid), and 7-hydroxylimononic acid L6' (7-hydroxy-3-isopropenyl- 6-oxoheptanoic acid) from limonene. A series of smog chamber experiments have been conducted in which five cyclic monoterpenes were oxidized by ozone. The evolved secondary aerosol was analyzed by GC-MS and HPLC-MS for nonvolatile polar oxidation products with emphasis on the identification of carboxylic acids. Three classes of compounds were determined at concentration levels corresponding to low percentage molar yields: i.e. dicarboxylic acids, oxocarboxylic acids, and hydroxyketocarboxylic acids. Carboxylic acids are highly polar and have lower vapor pressures than their corresponding aldehydes and may thus play an important role in secondary organic aerosol formation processes. The most abundant carboxylic acids were the following: cis-pinic acid AB1 (cis-3-carboxy-2,2-dimethylcyclobutylethanoic acid) from α- and β-pinene; cis-pinonic acid A3 (cis-3-acetyl-2,2-dimethylcyclobutylethanoic acid) and cis-10-hydroxypinonic acid AB6 (cis-2,2-dimethyl-3-hydroxyacetylcyclobutyl-ethanoic acid) from α-pinene and β-pinene; cis-3-caric acid C1 (cis-2,2-dimethyl-1,3-cyclopropyldiethanoic acid), cis-3-caronic acid C3 (2,2-dimethyl-3-(2-oxopropyl)cyclopropanylethanoic acid), and cis-10-hydroxy-3-caronic acid C6 (cis-2,2-dimethyl-3-(hydroxy-2-oxopropyl)cyclopropanyl-ethanoic acid) from 3-carene; cis-sabinic acid S1 (cis-2-carboxy-1-isopropylcyclopropylethanoic acid) from sabinene; limonic acid L1 (3-isopropenylhexanedioic acid), limononic acid L3 (3-isopropenyl-6-oxo-heptanoic acid), 7-hydroxy-limononic acid L6 (3-isopropenyl-7-hydroxy-6-oxoheptanoic acid), and 7-hydroxylimononic acid L6′ (7-hydroxy-3-isopropenyl-6-oxoheptanoic acid) from limonene.