4733-69-1

Usage

Uses

Used in Pharmaceutical Industry:
Furo[3,4-b]pyridin-5(7H)-one is utilized as a key intermediate in the synthesis of potential bioactive molecules for the development of new pharmaceuticals. Its unique structure and reactivity make it a promising candidate for the creation of innovative drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, furo[3,4-b]pyridin-5(7H)-one is employed as a precursor in the synthesis of novel agrochemicals. Its potential as a building block for the development of more effective and environmentally friendly crop protection products is currently being explored.
Research on furo[3,4-b]pyridin-5(7H)-one is focused on uncovering its pharmacological and pesticidal properties, with the ultimate goal of creating new and improved drugs and agricultural products that can benefit both human health and food security.

InChI:InChI=1/C7H5NO2/c9-7-5-2-1-3-8-6(5)4-10-7/h1-3H,4H2

Upstream product

• 89-00-9 Pyridine-2,3-dicarboxylic acid 
• 108-24-7 acetic anhydride 
• 38070-79-0 2,3-bis(hydroxymethyl)pyridine 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 4663-93-8 pyridine-2,3-dicarbaldehyde 

Downstream Products

• 81675-17-4 (1-Benzenesulfonyl-1H-indol-2-yl)-(3-hydroxymethyl-pyridin-2-yl)-methanone 
• 1311295-60-9 C₁₄H₁₃NO₃ 
• 1311295-67-6 C₃₀H₄₇N₃O₇Si₂ 
• 1311295-63-2 C₂₁H₃₄N₂O₄Si 
• 1311295-61-0 benzyl 3-(((tert-butyldimethylsilyl)oxy)methyl)picolinate 
• 693271-27-1 3-[(4-methoxyphenoxy)methyl]pyridine-2-carboxylic acid 
• 216658-54-7 3-(3-Chloro-phenoxymethyl)-pyridine-2-carboxylic acid 
• 55942-66-0 3-(phenoxymethyl)pyridine-2-carboxylic acid 

Relevant academic research and scientific papers

Efficient and Selective Cu/Nitroxyl-Catalyzed Methods for Aerobic Oxidative Lactonization of Diols

Cu/nitroxyl catalysts have been identified that promote highly efficient and selective aerobic oxidative lactonization of diols under mild reaction conditions using ambient air as the oxidant. The chemo- and regioselectivity of the reaction may be tuned by changing the identity of the nitroxyl cocatalyst. A Cu/ABNO catalyst system (ABNO = 9-azabicyclo[3.3.1]nonan-N-oxyl) shows excellent reactivity with symmetrical diols and hindered unsymmetrical diols, whereas a Cu/TEMPO catalyst system (TEMPO = 2,2,6,6-tetramethyl-1-piperidinyl-N-oxyl) displays excellent chemo- and regioselectivity for the oxidation of less hindered unsymmetrical diols. These catalyst systems are compatible with all classes of alcohols (benzylic, allylic, aliphatic), mediate efficient lactonization of 1,4-, 1,5-, and some 1,6-diols, and tolerate diverse functional groups, including alkenes, heterocycles, and other heteroatom-containing groups.

A practical strategy for the structural diversification of aliphatic scaffolds through the palladium-catalyzed picolinamide-directed remote functionalization of unactivated C(sp3)-H bonds

Hats off to the director: High levels of regio- and stereoselectivity were observed for a broad range of amine substrates with aryl and vinyl iodide coupling partners in the title reaction. The synthetic utility of this strategy was highlighted by the rea

Dual fluorescent N-Aryl-2,3-naphthalimides: Applications in ratiometric DNA detection and white organic light-emitting devices

A ten element matrix of 5- and 6-substituted-(2,3)-naphthalimides was prepared for the appropriate placement of substituents necessary to promote dual fluorescence (DF). As prescribed by our balanced seesaw photophysical model this matrix yielded nine new DF dyes out of a possible ten compounds. From this set of nine DF dyes, 4-fluoronaphthalic amide (37) was selected as a probe for ratiometric detection of DNA and demonstration of panchromatic emission.

Synthesis of the Pyridine Analogues of Phthalide

Routes for the preparation of the four isomeric pyridine analogues of phthalide are described starting from the readily available pyridine 2,3- and 3,4-diacids, or derivatives, and making use of the differential reactivity of substituents at pyridine 2- versus 3- and 3- versus 4-positions.