473432-11-0

Basic information

• Product Name: (2R,3S,6S)-2-butyl-6-methoxy-3,6-dihydro-2H-pyran-3-yl 4-methoxybenzoate
• CAS NO: 473432-11-0
• Molecular Weight: 320.386
• Mol File: 473432-11-0.mol

Chemical Properties

• CAS DataBase Reference: (2R,3S,6S)-2-butyl-6-methoxy-3,6-dihydro-2H-pyran-3-yl 4-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,6S)-2-butyl-6-methoxy-3,6-dihydro-2H-pyran-3-yl 4-methoxybenzoate(473432-11-0)
• EPA Substance Registry System: (2R,3S,6S)-2-butyl-6-methoxy-3,6-dihydro-2H-pyran-3-yl 4-methoxybenzoate(473432-11-0)

Safety Data

• Hazardous Substances Data: 473432-11-0(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 

Relevant articles and documents

Towards complete stereochemical control: Complementary methods for the synthesis of six diastereoisomeric monosaccharide mimetics

Complementary methods for the synthesis of diastereomeric monosaccharide mimetics are described which rely on the functionalisation of derivatives of 2-butyl-6-methoxy-2,6-dihydropyran-3-one. The stereochemical outcome of dihydroxylation of these derivatives under Upjohn's and Donohoe's (directed) reaction conditions are described. The hydrolyses of diastereomeric 2-butyl-4,5-epoxy-3-hydroxy-6-methoxytetrahydropyrans, generated either by epoxidation with perbenzimidic acid or by cyclisation of the corresponding hydroxy iodides, are described in detail. These methods have enabled stereoselective syntheses of six of a possible eight (ignoring anomers) diastereoisomers of 3,4,5-triacetoxy-2-butyl-6-methoxytetrahydropyran. The power of the general approach lies in the ability to choose at a late stage in the synthesis which diastereoisomer is prepared.